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Medications and Drugs

Brand Names: Capital with Codeine Suspension, Cocet, Cocet Plus, EZ III, Tylenol with Codeine #3, Tylenol with Codeine #4, Vopac

Generic Name: acetaminophen and codeine (Pronunciation: a SEET a MIN o fen and KOE deen)

What is acetaminophen and codeine (Capital with Codeine Suspension, Cocet, Cocet Plus, EZ III, Tylenol with Codeine #3, Tylenol with Codeine #4, Vopac)?

Codeine is in a group of drugs called narcotic pain relievers. Acetaminophen is a less potent pain reliever that increases the effects of codeine.

The combination of acetaminophen and codeine is used to relieve moderate to severe pain.

Acetaminophen and codeine may also be used for other purposes not listed in this medication guide.

Acetaminophen-Codeine 300 mg-15 mg-MAL

round, white, imprinted with 2, M inside square

Acetaminophen-Codeine 300 mg-30 mg-MAL

round, white, imprinted with 3, M inside square

Acetaminophen-Codeine 300 mg-30 mg-RAN

round, white, imprinted with 3, RX 562

Acetaminophen-Codeine 300 mg-60 mg-MAL

round, white, imprinted with 4, M inside square

Acetaminophen-Codeine 300 mg-60 mg-RAN

round, white, imprinted with 4, RX 561

APAP 2-BAR

round, white, imprinted with b 302, 2

APAP 2-TEV

round, white, imprinted with 93 50, 2

APAP 3-BAR

round, white, imprinted with b 303, 3

APAP 3-QUA

round, white, imprinted with 2064 V, 3

APAP 3-TEV

round, white, imprinted with 93 150, 3

APAP 4-BAR

round, white, imprinted with B 304, 4

APAP 4-TEV

round, white, imprinted with 93 350, 4

Tylenol 3

round, white, imprinted with TYLENOL CODEINE 3, McNEIL

What are the possible side effects of acetaminophen and codeine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • shallow breathing, slow heartbeat;
  • feeling light-headed, fainting;
  • confusion, unusual thoughts or behavior;
  • seizure (convulsions);
  • easy bruising or bleeding; or
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects include:

  • feeling dizzy or drowsy;
  • mild nausea, vomiting, upset stomach, constipation;
  • headache;
  • blurred vision; or
  • dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetaminophen and codeine?

Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take acetaminophen.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

Codeine may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

Acetaminophen and codeine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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