Font Size
A
A
A
...
8
...

Acid Reflux Disease (GERD) (cont.)

Acid Reflux (GERD) Medications

These drugs use different mechanisms to reduce reflux.

Proton pump inhibitors (PPIs)

Coating agents

Sucralfate (Carafate) coats mucous membranes and sores to provide an additional protective barrier against stomach acid.

Promotility agents

  • Promotility agents include metoclopramide (Reglan, Clopra, Maxolon) and bethanechol (Duvoid, Urabeth, Urecholine).
  • They help tighten the lower esophageal sphincter and promote faster emptying of the stomach.
  • Health-care professionals often are reluctant to prescribe these medications because they have fairly significant side effects.
  • Promotility agents also do not work as well as PPIs for most people.
  • One of these agents, cisapride (Propulsid), has been removed from the US market because of safety concerns related to lethal drug interactions.
Medically Reviewed by a Doctor on 8/28/2014
Medical Author:

Must Read Articles Related to Acid Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD) FAQs
Gastroesophageal Reflux Disease (GERD) FAQs Acid reflux (GERD) is caused by lifestyle factors (alcohol, obesity), medication, diet, medical conditions, and eating habits. Symptoms of acid reflux (GERD) in...learn more >>
Heartburn FAQs
Heartburn FAQs Heartburn FAQ including information about the causes of heartburn, lifestyle changes to reduce heartburn, OTC and prescription medications to decrease heartburn...learn more >>
GERD and Heartburn Medications
Understanding Heartburn/GERD Medications GERD and heartburn medications include antacids, histamine-2 blockers, proton pump inhibitors (PPIs), coating drugs, and promotility drugs. Side effects, drug i...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Acid Reflux (GERD):

GERD - Medical Treatment

What medical treatments have been effective in treating your case of GERD or acid reflux?

GERD - Symptoms and Signs

What were your GERD symptoms and signs?

GERD - Medications

What over-the-counter or prescription medications have been effective in treating your case of GERD?

GERD - Home Remedies

What lifestyle changes or home changes have you made that have been successful in managing GERD?




Read What Your Physician is Reading on Medscape

Gastroesophageal Reflux Disease »

Gastroesophageal reflux is a normal physiological phenomenon experienced intermittently by most people, particularly after a meal.

Read More on Medscape Reference »


Medical Dictionary