Acne Glossary of Terms

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Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).

Acne: Localized skin inflammation as a result of overactivity of the oil glands at the base of hair follicles. Acne happens when oil (sebaceous) glands come to life around puberty, when these glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls.
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Acne rosacea: This term is actually a misnomer! The appropriate term is simply rosacea which is a chronic skin disease that affects the middle third of the face with persistent redness over the areas of the face and nose that normally blush: mainly the forehead, the chin and the lower half of the nose. The tiny blood vessels in these areas enlarge (dilate) and become more visible through the skin, appearing like tiny red lines (called telangiectasias). Pimples can occur that look like teenage acne.
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Acne vulgaris: The common form of acne seen most often in teenagers or young adults, acne vulgaris is the result of overactive oil glands that become plugged, red, and inflamed. Most outbreaks of acne can be treated by keeping the skin clear and avoiding irritating soaps, foods, drinks, and cosmetics. Severe acne and acne in those who are prone to scarring (see the article on Keloid) can be treated with topical creams and anti-inflammatory medications. Skin damaged by acne can be improved with treatment by a dermatologist or facial technologist. Techniques include dermabrasion ("sanding"), removal of scar tissue via laser, and chemical peels. Acne is also called pimples.

Anatomy: The study of form. Gross anatomy involves structures that can be seen with the naked eye. It is as opposed to microscopic anatomy (or histology) which involves structures seen under the microscope. Traditionally, both gross and microscopic anatomy have been studied in the first year of medical school in the U.S. The most celebrated textbook of anatomy in the English-speaking world is Gray's Anatomy, still a useful reference book. The word "anatomy" comes from the Greek ana- meaning up or through + tome meaning a cutting. Anatomy was once a "cutting up" because the structure of the body was originally learned through dissecting it, cutting it up. The abbreviation for anatomy is anat.

Antibiotic: A drug used to treat infections caused by bacteria and other microorganisms. Originally, an antibiotic was a substance produced by one microorganism that selectively inhibits the growth of another. Synthetic antibiotics, usually chemically related to natural antibiotics, have since been produced that accomplish comparable tasks.
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Arms: An appendage in anatomy and in clinical trials. See: Arm.

Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Birth control: Birth control is the use of any practices, methods, or devices to prevent pregnancy from occurring in a sexually active woman. Also referred to as family planning, pregnancy prevention, fertility control, or contraception; birth control methods are designed either to prevent fertilization of an egg or implantation of a fertilized egg in the uterus.
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Blackhead: A familiar term for what is medically called an open comedo. A comedo, the primary sign of acne, consists of a dilated (widened) hair follicle filled with keratin squamae (skin debris), bacteria, and sebum (oil).
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Bowel: Another name for the intestine. The small bowel and the large bowel are the small intestine and large intestine, respectively.
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Chest: The area of the body located between the neck and the abdomen. The chest contains the lungs, the heart and part of the aorta. The walls of the chest are supported by the dorsal vertebrae, the ribs, and the sternum.
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Comedo: The primary sign of acne consisting of a dilated (widened) hair follicle filled with keratin squamae (skin debris), bacteria, and sebum (oil). A comedo may be closed or open.
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Comedones: The plural of comedo, the primary sign of acne, consisting of a dilated (widened) hair follicle filled with keratin squamae (skin debris), bacteria, and sebum (oil). Comedones may be closed or open.
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Depression: An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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Dermabrasion: Dermabrasion is a surgical procedure that involves the controlled abrasion (wearing away) of the upper layers of the skin with sandpaper or other mechanical means.
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Dermatologic: Having to do with the skin.

Dermatology: 1. The branch of medicine concerned with the diagnosis, treatment, and prevention of diseases of the skin, hair, nails, oral cavity and genitals. 2. Sometimes also, cosmetic care and enhancement.
Dermatology is literally the study of the skin.

Diagnosis: 1 The nature of a disease; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies. 3 The identification of any problem. The diagnosis was a plugged IV.
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Dilation: The process of enlargement, stretching, or expansion. The word "dilatation" means the same thing. Both come from the Latin "dilatare" meaning "to enlarge or expand."

Emergency department: The department of a hospital responsible for the provision of medical and surgical care to patients arriving at the hospital in need of immediate care. Emergency department personnel may also respond to certain situations within the hospital such cardiac arrests.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction.
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Estrogen: Estrogen is a female hormone produced by the ovaries. Estrogen deficiency can lead to osteoporosis.
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Estrogens: Female hormones produced by the ovaries. Estrogen deficiency can lead to osteoporosis.
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Exacerbate: To make worse. For example, smoking may exacerbate systemic lupus erythematosus.

Fever: Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Folliculitis: An infection of the hair follicles of the skin. Infection of the hair follicles can occur when the skin is disrupted or inflamed due to a number of conditions, including acne, skin wounds or injuries, friction from clothing, excessive sweating, or exposure to toxins. The symptoms vary and include small, red bumps or blisters around hair follicles, blisters filled with pus, or itching and tenderness of the involved area. When the deeper parts of the hair follicle are infected, a painful lump or mass may be felt.
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Genetic: Having to do with genes and genetic information.

Gland: 1. A group of cells that secrete a substance for use in the body. For example, the thyroid gland. 2. A group of cells that removes materials from the circulation. For example, a lymph gland.

Hair follicle: A sac from which a hair grows and into which the sebaceous (oil) glands open. The follicle is lined by cells derived from the epidermal (outside) layer of the skin.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Inflammation: A basic way in which the body reacts to infection, irritation or other injury, the key feature being redness, warmth, swelling and pain. Inflammation is now recognized as a type of nonspecific immune response.
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Inflammatory bowel disease: A group of chronic intestinal diseases characterized by inflammation of the bowel -- the large or small intestine. The most common types of inflammatory bowel disease (IBD) are ulcerative colitis and Crohn disease.
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Lipids: Another word for "fats." (Please see the various meanings of Fat.) Lipids can be more formally defined as substances such as a fat, oil or wax that dissolves in alcohol but not in water. Lipids contain carbon, hydrogen and oxygen but have far less oxygen proportionally than carbohydrates.
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Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.

Menstrual: Pertaining to menstruation (the menses), as in last menstrual period, menstrual cramps, menstrual cycle, and premenstrual syndrome. From the Latin menstrualis, from mensis meaning month.

Menstrual cycle: The monthly cycle of changes in the ovaries and the lining of the uterus (endometrium), starting with the preparation of an egg for fertilization. When the follicle of the prepared egg in the ovary breaks, it is released for fertilization and ovulation occurs. Unless pregnancy occurs, the cycle ends with the shedding of part of the endometrium, which is menstruation. Although it is actually the end of the physical cycle, the first day of menstrual bleeding is designated as "day 1" of the menstrual cycle in medical parlance.

Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.

Nodular: Bumpy.

Papules: Small solid rounded bumps rising from the skin that are each usually less than 1 centimeter in diameter (less than 3/8 inch across).
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.

Pimples: Small papules or pustules. See: Pimple.

Pregnant: The state of carrying a developing fetus within the body.
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Prognosis: 1. The expected course of a disease.
2. The patient's chance of recovery.
The prognosis predicts the outcome of a disease and therefore the future for the patient. His prognosis is grim, for example, while hers is good.
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Propionibacterium acnes: A ubiquitous skin-dwelling organism that is involved in causing acne.In addition to acne, this bacterium (P. acnes) is associated with corneal ulcers, endocarditis, sarcoidosis, cholesterol gallstones, allergic alveolitis, pulmonary angiitis, and the SAPHO syndrome (of Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis).
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Puberty: A complex biologic and psychologic process involving sexual development, accelerated growth, and adrenal maturation heralded by the secretion of gonadotropin releasing hormone (GnRH) from a part of the brain called the hypothalamus. This event is the first known step in the reproductive cascade. It initiates the pulsatile release of gonadotropins, gonadal secretion of sex steroids, pubertal development, and gametogenesis (the production of sperm and ova).
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Rash: Breaking out (eruption) of the skin. Medically, a rash is referred to as an exanthem.

Remission: Disappearance of the signs and symptoms of cancer or other disease. When this happens, the disease is said to be "in remission." A remission can be temporary or permanent.

Retinoid: 1. Vitamin A (retinol) or a naturally occurring or synthetic substance chemically related to it. (Retinoid literally means "like retinol.")
2. In ophthalmology, resembling the retina.

Rosacea: A chronic skin disease that affects the middle third of the face with persistent redness over the areas of the face and nose that normally blush: mainly the forehead, the chin and the lower half of the nose. The tiny blood vessels in these areas enlarge (dilate) and become more visible through the skin, appearing like tiny red lines (called telangiectasias). Pimples can occur that look like teenage acne.
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Rupture: A break or tear in any organ (such as the spleen) or soft tissue (such as the achilles tendon). Rupture of the appendix is more likely among uninsured and minority children when they develop appendicitis.

Sebaceous gland: A normal gland of the skin which empties an oily secretion into the hair follicle near the surface of the skin.

Sebum: An oily secretion of the sebaceous gland which helps to preserve the flexibility of the hair.

Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.

Steroid: A general class of chemical substances that are structurally related to one another and share the same chemical skeleton (a tetracyclic cyclopenta[a]phenanthrene skeleton).
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body.

Tetracycline: A family of broad-spectrum antibiotics effective against a remarkably wide variety of organisms. Bacteria susceptible to teracycline include H. flu (Hemophilus influenzae), strep (Streptococcus pneumoniae), Mycoplasma pneumoniae, Chlamydia psittaci, Chlamydia trachomatis, and Neisseria gonorrhoeae (the cause of gonorrhea). Tetracycline is also used to treat nongonococcal urethritis (due to Ureaplasma), Rocky mountain spotted fever, typhus, chancroid, cholera, brucellosis, anthrax, and syphilis. It is used in combination with other medications to treat Helicobacter pylori, the bacteria associated with ulcers of the stomach and duodenum.
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Therapy: The treatment of disease.
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Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.

Vitamin A: Vitamin A is retinol. Carotene compounds (found, for example, in egg yolk, butter and cream) are gradually converted by the body to vitamin A (retinol). A form of vitamin A called retinal is responsible for transmitting light sensation in the retina of the eye.
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Whitehead: A familiar term for what is medically called a closed comedo.
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Zinc: A mineral essential to the body, zinc is a constituent of many enzymes that permit chemical reactions to proceed at normal rates. It is involved in the manufacture of protein (protein synthesis) and in cell division. Zinc is also a constituent of insulin, and is concerned with the sense of smell.
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