Most people do not know they have acromegaly until the disease is advanced. Signs of acromegaly often develop so gradually that they go unnoticed for years or even decades.

The most common symptom is enlargement of the hands or feet. You may notice that your rings are becoming too small, a sign that your hands are growing larger. You may need to buy larger shoes.

Your jaw, forehead, and other parts of the face also may enlarge. This changes the way you look. Because this growth happens slowly over time, many people, including your primary care doctor, may not notice the change in your appearance. Often, a friend or relative you haven’t seen in a few years or a new consulting doctor notices the change.

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