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Activated

Activated Charcoal Overview

It was 1831. In front of his distinguished colleagues at the French Academy of Medicine, Professor Touery drank a lethal dose of strychnine and lived to tell the tale. He had combined the deadly poison with activated charcoal.

That's how powerful activated charcoal is as an emergency decontaminant in the gastrointestinal (GI) tract, which includes the stomach and intestines. Activated charcoal is considered to be the most effective single agent available. It is used after a person swallows or absorbs almost any toxic drug or chemical.

  • Activated charcoal is estimated to reduce absorption of poisonous substances up to 60%.

  • It works by adsorbing chemicals, thus reducing their toxicity (poisonous nature), through the entire length of the stomach and small and large intestines (GI tract).

  • Activated charcoal itself is a fine, black powder that is odorless, tasteless, and nontoxic.

  • Activated charcoal is often given after the stomach is pumped (gastric lavage). Gastric lavage is only effective immediately after swallowing a toxic substance (within about one-half hour) and does not have effects that reach beyond the stomach as activated charcoal does.


Next: How Activated Charcoal Works »

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Activated Charcoal

Aspirin Poisoning Overview

Aspirin is a trade name for acetylsalicylic acid, a common pain reliever (also called an analgesic). The earliest known uses of the drug can be traced back to the Greek physician Hippocrates in the fifth century BC. He used powder extracted from the bark of willows to treat pain and reduce fever.

  • Salicin, the parent of the salicylate drug family, was successfully isolated from willow bark in 1829. Sodium salicylate, a predecessor to aspirin, was developed, along with salicylic acid, as a pain reliever in 1875.
  • Sodium salicylate was not often popular though, because it irritated the stomach. However, in 1897, Felix Hoffman changed the face of medicine forever. Hoffman was a German chemist working for Bayer. He had been using the common pain reliever of the time, sodium salicylate, to treat his father's arthritis. The sodium salicylate caused his father the same stomach trouble it caused other people, so Hoffman a...

Read the Aspirin Poisoning article »


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Toxicity, Barbituate »

Barbiturates are the earliest class of sedative-hypnotic agents to be developed and were once extremely popular drugs of abuse. 

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