font size
A
A
A

Androstenedione

How does Androstenedione work?

Androstenedione is a steroid hormone used by the body to make testosterone and estrogen.

Are there safety concerns?

Androstenedione is POSSIBLY UNSAFE for most people when taken by mouth. Some side effects experienced by men include reduced sperm production, shrunken testicles, painful or prolonged erections, breast development, behavioral changes, heart disease, and others. Women might develop masculine traits including deepening of the voice, facial hair, acne, male-pattern baldness, and coarsening of the skin. Women may also experience abnormal menstrual periods and depression. Androstenedione can increase the chances of getting cancers of the breast, prostate, or pancreas; and it is poisonous to the liver.

There is some concern that the strength and purity of androstenedione products may not match the product labeling.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Androstenedione is LIKELY UNSAFE to use during pregnancy. It might bring on labor and cause a miscarriage.

Not enough is known about the safety of using androstenedione during breast-feeding. Stay on the safe side and avoid use.

Children: In children, androstenedione is LIKELY UNSAFE as it might stop bone growth and lead to shorter adult height, as well as early onset of puberty.

Depression: There is concern that androstenedione supplements might make depression worse in women. This s because some women with severe major depression have naturally high levels of androstenedione, so some people think there may be a connection. However, it is not known if taking androstenedione supplements causes depression.

Hormone-sensitive cancers and conditions: Androstenedione is the steroid hormone used by the body to make testosterone and estrogen. Taking androstenedione seems to increase estrogen levels. Men and women with hormone sensitive conditions should avoid androstenedione. Some of these conditions include breast, uterine, ovarian, and prostate cancer; endometriosis; and uterine fibroids.

Liver disease: There is some concern that androstenedione might harm the liver. So far, no such cases have been reported, but steroids similar to androstenedione have been connected to liver problems. Don't take androstenedione if you have any type of liver disease. Even if you don't have liver disease, it's best to get liver function tests if you take androstenedione.

Prostate cancer: There is some concern that androstenedione might increase the chances of developing prostate cancer. Developing research suggests that androstenedione can encourage prostate tumor cell growth. Don't use androstenedione if you have prostate cancer.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Therapeutic Research Faculty copyright

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.



Medical Dictionary