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Ankylosing Spondylitis, Orthopedic Perspective (cont.)

AS Orthopedic Causes

The exact cause of ankylosing spondylitis remains unknown. A possible genetic link exists, as the risk of developing ankylosing spondylitis or any other seronegative spondyloarthropathy increases when a family member has the condition.

Ankylosing spondylitis and the other spondyloarthropathies have also been linked to a specific protein, HLA-B27, in a person's blood. If this protein is present, the risk of developing ankylosing spondylitis is multiplied 10 times. The specific role this protein plays in the development of ankylosing spondylitis is unclear.

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Ankylosing Spondylitis »

Ankylosing spondylitis (AS) is a chronic, multisystem inflammatory disorder of the sacroiliac (SI) joints and the axial skeleton.

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