Ankylosing Spondylitis, Orthopedic Perspective (cont.)
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AS Orthopedic Causes
The exact cause of ankylosing spondylitis remains unknown. A possible genetic link exists, as the risk of developing ankylosing spondylitis or any other seronegative spondyloarthropathy increases when a family member has the condition.
Ankylosing spondylitis and the other spondyloarthropathies have also been linked to a specific protein, HLA-B27, in a person's blood. If this protein is present, the risk of developing ankylosing spondylitis is multiplied 10 times. The specific role this protein plays in the development of ankylosing spondylitis is unclear.
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