Font Size
A
A
A

Ankylosing Spondylitis, Orthopedic Perspective (cont.)

AS Orthopedic Symptoms

Patient Comments

Patients with AS develop low back pain, hip pain, and stiffness, or both. Later, patients develop upper back pain and pain in the ribs. Symptoms most commonly begin in late adolescence, and males are three times more likely to develop ankylosing spondylitis than females. It is uncommon for patients over 45 years old to develop AS. If symptoms begin in those younger than 16 years, the disease is termed juvenile-onset ankylosing spondylitis, which is more common in Native Americans and in people who live in developing countries.

People with ankylosing spondylitis generally complain of back pain of gradual onset that may not become apparent until the condition is well established. The pain progresses with a series of flare-ups and remissions. The back pain is dull and is felt in the hips and buttocks. The pain often begins on one side (unilateral) and comes and goes (intermittent), but as the disease progresses, it becomes more persistent and affects both sides (bilateral).

Key components of a person's medical history that suggest ankylosing spondylitis include the following:

  • Gradual onset of low back pain
  • Onset of symptoms prior to age 40 years
  • Presence of symptoms for more than three months
  • Symptoms worse in the morning or with inactivity
  • Improvement of symptoms (especially morning stiffness) with exercise

Involvement of the hips and shoulder joints is possible but is more common in juvenile-onset ankylosing spondylitis (patients with onset before age 16 years).

Involvement of the jaw (temporomandibular joint, TMJ) can lead to decreased range of motion in the jaw and occurs in some people with ankylosing spondylitis.

Involvement of the ribs can lead to decreased range of motion of the chest wall and difficulty expanding the lungs during breathing.

Long-term involvement of the spine eventually leads to a progressive decrease in range of motion. Eventually, the bones of the spine grow together and prevent any motion in the affected bones of the back and neck. Involvement of the neck (cervical spine) and upper back (thoracic spine) can lead to fusion of the neck in a downward position (forward flexed) . Fusion of the neck in this position can significantly limit a person's ability to walk because of an inability to look straight ahead or to drive a car without adaptive mirrors because of difficulty turning the head.

Other complications include the following:

  • Inflammation of the iris, the colored part of the eye (acute iritis): Acute iritis occurs in some people with ankylosing spondylitis and generally only affects one eye. Symptoms include pain, increased tearing (lacrimation), sensitivity to light (photophobia), and blurred vision.
  • Inflammation of the aorta, the major blood vessel from the heart (aortitis) and stiffening of the blood vessels (aortic fibrosis): Involvement of the heart is generally occurs in patients that have had AS for a long time. Severe cases can lead to complete heart block or weakening of the aortic valve (aortic valve insufficiency).
  • Stiffening of the lungs (pulmonary fibrosis): Involvement of the lungs is made worse by stiffening of the rib joints that limits range of motion of the chest wall. Pulmonary fibrosis generally produces no symptoms. If a chest X-ray film is obtained for another reason, pulmonary fibrosis is a finding that may also show up on the film.
  • Decreased function of the brain, spinal cord, muscles, and nerves (neurologic deficit): Neurologic deficits can be caused by spinal fracture or cauda equina syndrome due to narrowing of the spinal canal (spinal stenosis). Spinal fracture is most common in the neck (cervical spine).
Medically Reviewed by a Doctor on 8/15/2014

Must Read Articles Related to Ankylosing Spondylitis, Orthopedic Perspective

Ankylosing Spondylitis, Neurologic Perspective
Ankylosing Spondylitis, Neurologic Perspective Ankylosing spondylitis (AS) is a long-term disease that affects the joints near the center of the body, especially the spine and sacroiliac joints. Symptoms inc...learn more >>
Ankylosing Spondylitis, Ophthalmologic Perspective
Ankylosing Spondylitis, Ophthalmologic Perspective Ankylosing spondylitis (AS) is a type of progressive arthritis that leads to chronic inflammation of the spine and the area where the spine joins the pelvis (sa...learn more >>
Ankylosing Spondylitis, Radiologic Perspective
Ankylosing Spondylitis, Radiologic Perspective Ankylosing spondylitis (AS) is a type of progressive arthritis that leads to chronic inflammation of the spine and the area where the spine joins the pelvis (sa...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Ankylosing Spondylitis, Orthopedic Perspective:

Ankylosing Spondylitis - Symptoms

What symptoms of Ankylosing Spondylitis have you experienced?

Ankylosing Spondylitis - Symptoms

What treatment did you receive for Ankylosing Spondylitis?

close

From Our Sponsor

Content under this heading is from or created on behalf of the named sponsor. This content is not subject to the WebMD Editorial Policy and is not reviewed by the WebMD Editorial department for accuracy, objectivity or balance.



From WebMD


Read What Your Physician is Reading on Medscape

Ankylosing Spondylitis »

Ankylosing spondylitis (AS) is a chronic, multisystem inflammatory disorder of the sacroiliac (SI) joints and the axial skeleton.

Read More on Medscape Reference »


Medical Dictionary