Antidepressants for Migraine Headaches
Antidepressant medicines, which are usually used to treat
Tricyclic antidepressants are used most to prevent migraines. Amitriptyline and nortriptyline are used most often. Both have been shown to be effective in preventing
Other tricyclic antidepressants may be tried if you do not respond well to amitriptyline or nortriptyline. The choice of antidepressant to treat your migraines may depend on your ability to tolerate the side effects of the medicine.
Side effects of tricyclic antidepressants include:
The U.S. Food and Drug Administration (FDA) has issued an
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