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May 25, 2013

antidiabetics-oral Glossary of Terms

The following are health and medical definitions of terms that appear in the antidiabetics-oral article.

Allergic reaction: The hypersensitive response of the immune system of an allergic individual to a substance.
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Blindness: Loss of useful sight. Blindness can be temporary or permanent. Damage to any portion of the eye, the optic nerve, or the area of the brain responsible for vision can lead to blindness. There are numerous (actually, innumerable) causes of blindness. The current politically correct terms for blindness include visually handicapped and visually challenged.

Blood glucose: The main sugar that the body makes from the food in the diet. Glucose is carried through the bloodstream to provide energy to all cells in the body. Cells cannot use glucose without the help of insulin.
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".

Blood sugar: Blood glucose. See also: High blood sugar; Low blood sugar.

Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction and then exhaled due to muscle relaxation.

Chills: feelings of coldness accompanied by shivering. Chills may develop after exposure to a cold environment or may accompany a fever.

Circulation: In medicine, the movement of fluid through the body in a regular or circuitous course. The circulatory system, composed of the heart and blood vessels, functions to produce circulation. Heart failure is an example of a problem with circulation.

Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus. Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
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Diarrhea: A common condition that involves unusually frequent and liquid bowel movements. The opposite of constipation. There are many infectious and noninfectious causes of diarrhea. Persistent diarrhea is both uncomfortable and dangerous to the health because it can indicate an underlying infection and may mean that the body is not able to absorb some nutrients due to a problem in the bowels. Treatment includes drinking plenty of fluids to prevent dehydration and taking over-the-counter remedies. People with diarrhea that persists for more than a couple days, particularly small children or elderly people, should seek medical attention.

Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo.
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Fasting: : going without food or drink. Patients may be advised to fast for a certain period of time prior to surgery, medical procedures, or certain blood tests.

Fasting blood glucose: A test to determine how much glucose (sugar) is in a blood sample after an overnight fast. The fasting blood glucose test is commonly used to detect diabetes mellitus. A blood sample is taken in a lab, physician's office, or hospital. The test is done in the morning, before the person has eaten. The normal range for blood glucose is 70 to 100 mg/dl. Levels between 100 and 126 mg/dl are referred to as impaired fasting glucose or pre-diabetes. Diabetes is typically diagnosed when fasting blood glucose levels are 126 mg/dl or higher.

Fever: Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.

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Glaucoma: A common eye condition in which the fluid pressure inside the eyes rises because of slowed fluid drainage from the eye. If untreated, it may damage the optic nerve and other parts of the eye, causing the loss of vision or even blindness.
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Glucose: The simple sugar that is the chief source of energy. Glucose is found in the blood and is the main sugar that the body manufactures. The body makes glucose from all three elements of food'protein, fats, and carbohydrates'but the largest amount of glucose derives from carbohydrates. Glucose serves as the major source of energy for living cells. However, cells cannot use glucose without the help of insulin. Also known as dextrose.

Headache: A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. The heart is positioned in the chest behind the sternum (breastbone); in front of the trachea, esophagus, and aorta; and above the diaphragm. A normal heart is about the size of a closed fist and weighs about 298 grams or 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest, with the balance in the right side of the chest. The heart is composed of specialized cardiac muscle, and it is four-chambered, with a right atrium and ventricle, and an anatomically separate left atrium and ventricle. The blood flows from the systemic veins into the right atrium, thence to the right ventricle, from which it is pumped to the lungs and then returned into the left atrium, thence to the left ventricle, from which it is driven into the systemic arteries. The heart is thus functionally composed of two hearts: the right heart and the left heart. The right heart consists of the right atrium, which receives deoxygenated blood from the body, and the right ventricle, which pumps the deoxygenated blood to the lungs under low pressure; and the left heart, which consists of the left atrium, which receives oxygenated blood from the lung, and the left ventricle, which pumps the oxygenated blood out to the body under high pressure.

Heart disease: Any disorder that affects the heart. Sometimes the term "heart disease" is used narrowly and incorrectly as a synonym for coronary artery disease. Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels. Among the many types of heart disease, see, for example: Angina; Arrhythmia; Congenital heart disease; Coronary artery disease (CAD); Dilated cardiomyopathy; Heart attack (myocardial infarction); Heart failure; Hypertrophic cardiomyopathy; Mitral regurgitation; Mitral valve prolapse; and Pulmonary stenosis.

Heart rate: The number of heartbeats per unit of time, usually per minute. The heart rate is based on the number of contractions of the ventricles (the lower chambers of the heart). The heart rate may be too fast (tachycardia) or too slow (bradycardia). The pulse is a bulge of an artery from waves of blood that course through the blood vessels each time the heart beats. The pulse is often taken at the wrist to estimate the heart rate.

Hemoglobin: The oxygen-carrying pigment and predominant protein in the red blood cells. Hemoglobin forms an unstable, reversible bond with oxygen. In its oxygenated state it is called oxyhemoglobin and is bright red. In the reduced state it is called deoxyhemoglobin and is purple-blue.
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Hemoglobin A1c: A minor component of hemoglobin to which glucose is bound. Abbreviated HbA1c. HbA1c levels depend on the blood glucose concentration: The higher the glucose concentration in blood, the higher the level of HbA1c. Levels of HbA1c are not influenced by daily fluctuations in the blood glucose concentration but reflect the average glucose levels over the prior 6 to 8 weeks. Measurement of HbA1c is a useful indicator of how well the blood glucose level has been controlled in the recent past and may be used to monitor the effects of diet, exercise, and drug therapy on blood glucose in patients with diabetes. In healthy people without diabetes, the HbA1c level is less than 7 percent of total hemoglobin. Also known as glycosylated or glucosylated hemoglobin.

High blood pressure: A repeatedly elevated blood pressure exceeding 140 over 90 mmHg. Chronic high blood pressure can stealthily cause blood vessel changes in the back of the eye (retina), abnormal thickening of the heart muscle, kidney failure, and brain damage. No specific cause for high blood pressure is found in 95 percent of patients. Treatment for high blood pressure involves dietary changes, regular aerobic exercise, and medication. There are many types of medications used to treat high blood pressure including diuretics, beta-blockers, blood vessel dilators, and others. Also known as hypertension.

High blood sugar: An elevated level of the sugar glucose in the blood. Also called hyperglycemia.
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Hygiene: The science of preventive medicine and the preservation of health. Also commonly used as a euphemism for cleanliness and proper sanitation.

Hyperglycemia: A high blood sugar. An elevated level specifically of the sugar glucose in the blood.
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Hypoglycemia: Low blood sugar (glucose). Hypoglycemia may be associated with symptoms such as anxiety, sweating, tremor, palpitations, nausea, and pallor. Hypoglycemia also starves the brain of glucose energy, which is essential for proper brain function. Lack of glucose energy to the brain can cause symptoms ranging from headache, mild confusion, abnormal behavior, loss of consciousness, seizure, and coma. Severe hypoglycemia can cause death. The causes of hypoglycemia include use of drugs (such as insulin), liver disease, surgical absence of the stomach, tumors that release excess amounts of insulin, and pre-diabetes. In some patients, symptoms of hypoglycemia occur during fasting (fasting hypoglycemia). In others, symptoms of hypoglycemia occur after meals (reactive hypoglycemia). Immediate treatment of severe hypoglycemia consists of administering large amounts of glucose and repeating this treatment at intervals if the symptoms persist. Treatment must also be directed at the underlying cause. Treatment of reactive hypoglycemia involves changing the diet, including eating fewer concentrated sweets and ingesting multiple small meals throughout the day.

Insulin: A natural hormone made by the pancreas that controls the level of the sugar glucose in the blood. Insulin permits cells to use glucose for energy. Cells cannot utilize glucose without insulin.
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Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin and makes the person want to scratch the affected area. Itching is medically known as pruritis; something that is itchy is pruritic.

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Kidney: One of a pair of organs located in the right and left side of the abdomen. The kidneys remove waste products from the blood and produce urine. As blood flows through the kidneys, the kidneys filter waste products, chemicals, and unneeded water from the blood. Urine collects in the middle of each kidney, in an area called the renal pelvis. It then drains from the kidney through a long tube, the ureter, to the bladder, where it is stored until elimination. The kidneys also make substances that help control blood pressure and regulate the formation of red blood cells.

Laboratory: A place for doing tests and research procedures, and for preparing chemicals and some medications. Also known as lab.

Liver: The largest solid organ in the body, situated in the upper part of the abdomen on the right side. The liver has a multitude of important and complex functions, including to manufacture proteins, including albumin (to help maintain the volume of blood) and blood clotting factors; to synthesize, store, and process fats, including fatty acids (used for energy) and cholesterol; to metabolize and store carbohydrates (used as the source for the sugar in blood); to form and secrete bile that contains bile acids to aid in the intestinal absorption of fats and the fat-soluble vitamins A, D, E, and K; to eliminate, by metabolizing or secreting, the potentially harmful biochemical products produced by the body, such as bilirubin, from the breakdown of old red blood cells and ammonia from the breakdown of proteins; and to detoxify, by metabolizing and/or secreting, drugs, alcohol, and environmental toxins.

Low blood sugar: A low blood level of the sugar glucose. Also called hypoglycemia.
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Medical history: 1. In clinical medicine, the patient's past and present which may contain relevant information bearing on their health past, present, and future. The medical history, being an account of all medical events and problems a person has experienced is an important tool in the management of the patient.
2. The history of medicine.

MedicAlert: A nonprofit emergency medical information service, known for its MedicAlert jewelry, particularly the bracelet, and its 24-hour emergency response center.
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Nausea: Stomach queasiness, the urge to vomit. Nausea can be brought on by many causes, including systemic illnesses (such as influenza), medications, pain, and inner ear disease.

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pharmacist: A professional who fills prescriptions and, in the case of a compounding pharmacist, makes them. Pharmacists are very familiar with medication ingredients, interactions, and cautions.

Poison: Any substance that can cause severe organ damage or death if ingested, breathed in, or absorbed through the skin. Many substances that normally cause no problems, including water and most vitamins, can be poisonous if taken in excessive quantity. Poison treatment depends on the 'substance.

Poison control center: A special information center set up to inform people about how to respond to potential poisoning. These centers maintain databases of poisons and appropriate emergency treatment. Local poison control centers should be listed with other community-service numbers in the front of the telephone book, and they can also be reached immediately through any telephone operator.

Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Pregnant: The state of carrying a developing fetus within the body.
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Rash: Breaking out (eruption) of the skin. A rash can be caused by an underlying medical condition, hormonal cycles, allergies, or contact with irritating substances. Treatment depends on the underlying cause of the rash. Medically, a rash is referred to as an exanthem.

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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.

Sore: 1. (adjective) A popular term for painful, such as a sore throat. 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

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Sore throat: Pain in the throat. Sore throat may be caused by many different causes, including inflammation of the larynx, pharynx, or tonsils.
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Stomach: The digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine. When food enters the stomach, muscles in the stomach wall create a rippling motion (peristalsis) that mixes and mashes the food. At the same time, juices made by glands in the lining of the stomach help digest the food. After about 3 hours, the food becomes a liquid and moves into the small intestine, where digestion continues.

Sunburn: Sunburn is an inflammation of the skin that develops in response to exposure to ultraviolet (UV) radiation from the sun or from tanning beds and booths that emit UV radiation. Sunburn is manifested by reddened, painful skin that may develop blisters.
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Sunscreen: A substance that blocks the effect of the sun's harmful rays. Using lotions that contain sunscreens can reduce the risk of skin cancer, including melanoma.

Sweat: A colorless transparent acidic fluid with a distinctive odor secreted by the small tubular sudoriferous (sweat) glands situated within the skin and under it in the subcutaneous tissue. The sweat glands discharge their fluid through tiny openings in the surface of the skin.
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Sweating: The act of secreting fluid from the skin by the sweat (sudoriferous) glands. These are small tubular glands situated within and under the skin (in the subcutaneous tissue). They discharge by tiny openings in the surface of the skin.
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Therapy: The treatment of disease. Therapy is synonymous with treatment.

Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth, consisting anatomically of the pharynx and larynx. The throat contains the trachea and a portion of the esophagus.

Urine: Liquid waste produced by the kidneys. Urine is a clear, transparent fluid that normally has an amber color. The average amount of urine excreted in 24 hours is between 5 to 8 cups or 40 and 60 ounces. Chemically, urine is mainly a watery solution of salt and substances called urea and uric acid. Normally, it contains about 960 parts water to 40 parts solid matter. Abnormally, it may contain sugar (in diabetes), albumin (a protein, as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.

Warfarin: An anticoagulant drug (brand names: Coumarin, Panwarfin, Sofarin) taken to prevent the blood from clotting and to treat blood clots and overly thick blood. Warfarin is also used to reduce the risk of clots causing strokes or heart attacks.
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