An insulin reaction is an excessively low blood sugar level (hypoglycemia), usually lower than 50 mg/dL. Insulin reactions result from an excess of insulin via an injection or an excess of an insulin-stimulating oral hypoglycemic agent, usually in the sulfonylurea class of drugs. Insulin reactions are more common in people with severe diabetes. Hypoglycemia occurs more often when a person is attempting to achieve near normal blood sugar levels.
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