Medical Author: Benjamin C. Wedro, MD, FAAEM
Medical Editors: Melissa Conrad Stöppler, MD
Diabetes is pretty easy to understand. The body needs glucose (or sugar) as a
power source for metabolism. Insulin, a molecule made in the pancreas, acts as a
key to open cell doors and allow glucose to enter cells from the bloodstream and
allow the necessary power generation to happen. In healthy people, the pancreas
can help regulate blood sugar levels and make certain that cells get the energy
source they need. In people with diabetes, the system doesn't work; either the
pancreas doesn't make any insulin, doesn't make enough insulin, or makes insulin
that isn't effective. This causes blood sugar levels to rise, cells to
malfunction, and the body to break down.
The treatment of diabetes is theoretically easy. Balance the glucose intake in the diet with the amount of energy the body needs to do its chores, and then add medications by mouth or insulin injections to make it all happen. Reality isn't that easy, and for many people, poorly controlled diabetes leads to problems years later. Small blood vessels start to become narrow and fragile. Organs lose blood supply and begin to fail, slowly at first, but then life-threatening events can occur. Heart attacks, kidney failure, poor circulation in the feet (sometimes requiring amputation), and blindness are just some of the effects of blood sugar levels that remain chronically too high.
Diabetes mellitus is one of the leading causes of irreversible blindness worldwide, and, in the United States, it is the most common cause of blindness in people younger than 65 years of age.
In addition to being a leading cause of blindness, diabetic eye disease encompasses a wide range of problems that can affect the eyes.
Diabetes mellitus may also result in heart disease, stroke, kidney failure, and circulatory abnormalities of the legs.
The American Diabetes Association estimates that 20 million people in the United States have diabetes. One-third of this population is unaware of their illness. A recent change in the exact definitions of diabetes and "pre-diabetes" by an international expert committee leads to the estimate that an additional 41 million people in the United States (40% of adults aged 40-74 years) have "pre-diabetes," a condition that significantly increases their risk for developing diabetes.
This new definition underscores the importance for everyone to take steps to help prevent the development of this disease. Individuals can try to avoid the problems associated with diabetes mellitus, including those that affect the eyes, by taking appropriate care of themselves by:Lifestyle management has been shown to reduce the risk of developing type II diabetes and pre-diabetes by at least two-thirds. It can also slow or halt the progression of pre-diabetes to diabetes.
If you or someone you know has already been diagnosed with diabetes mellitus, the following steps should also be taken: 
| Printer-Friendly Format | | | Email to a Friend |
Find tips and advances in treatment.
Living with an Insulin Pump
After years of debilitating seizures, diabetic Melissa Jeffries regains control of her diabetes through the use of an insulin pump. See more WebMD Videos »
|