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Aspirin Poisoning (cont.)

Medications

Activated charcoal: To prevent more absorption, the doctor may give activated charcoal to absorb the salicylate from the stomach. A laxative may be given with the activated charcoal to move the mixture through the gastrointestinal system more rapidly. People who have been severely poisoned may be given repeated doses of activated charcoal.

IV fluids: Dehydration occurs early in aspirin poisoning. To correct dehydration, the doctor will start an IV to correct this imbalance. The doctor will also work to correct imbalances in the body's blood chemistries.

Alkaline diuresis: This is a way to reduce the amount of salicylate in the body. Alkaline diuresis is the process of giving a person who has been poisoned compounds that alter the chemistry of the blood and urine in a way that allows the kidneys to remove more salicylate. Specifically, sodium bicarbonate is given via IV to make the blood and urine less acidic (more alkaline), which encourages the kidneys to capture more salicylate that can leave the body through the urine. Sometimes, other compounds, such as potassium, also have to be given to help with this process and help prevent hypokalemia.

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Toxicity, Salicylate »

The use of salicylates dates back 2500 years to when Hippocrates recommended the use of willow bark to relieve the pain of childbirth.

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