BOTOX® Injections Preparation

The material BOTOX® comes as a crystalline substance from the manufacturer, which then has to be reconstituted with saline or another liquid. Practitioners add varying amounts of liquid when reconstituting it. Although there is no right or wrong amount of liquid to add, most physicians add about 2 or 3 mL (about a half a teaspoon) of liquid to each vial. Some add quite a bit more, which can lead patients to think they are getting more BOTOX® when, in reality, they are getting the same or less amount of BOTOX® than samples reconstituted in a stronger way. It is the total dose of medication, not the volume of liquid, that leads to the desired effect.