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May 24, 2013
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Brain Cancer

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Brain Cancer Overview

Cancers of the brain are the consequence of abnormal growths of cells in the brain. Brain cancers can arise from primary brain cells, the cells that form other brain components (for example, membranes, blood vessels), or from the growth of cancer cells that develop in other organs and that have spread to the brain by the bloodstream (metastatic brain cancer).

  • Although many growths in the brain are popularly called brain tumors, not all brain tumors are cancerous. Cancer is a term reserved for malignant tumors.
  • Malignant tumors grow and spread aggressively, overpowering healthy cells by taking their space, blood, and nutrients. Like all cells of the body, tumor cells need blood and nutrients to survive. This is especially a problem in the brain, as the added growth within the closed confines of the skull can lead to an increase in intracranial pressure or the distortion of surrounding vital structures, causing their malfunction.
  • Tumors that do not grow aggressively are called benign. Almost all tumors that begin in the brain do not spread to other parts of the body. The major difference between benign and malignant tumors is that malignant tumors can invade the brain tissues and grow rapidly. This rapid growth in the confines of the skull can quickly cause damage to nearby brain tissue.
  • In general, a benign tumor is less serious than a malignant tumor. However, a benign tumor can still cause many problems in the brain, but usually the problems progress at a slower rate than malignant tumors.

Sometimes people confuse brain aneurysms with brain tumors. Brain aneurysms are not tumors; they are areas in the brain arteries or veins that are abnormally weak and expand to form a ballooning or expansion of the vessel wall. They seldom produce any symptoms unless they begin to leak blood into the surrounding brain tissue. Aneurysms may be congenital (present at birth) or expanded or formed in brain vessels after vessel damage (for example, trauma, atherosclerosis, high blood pressure) but are not formed from cancer cells. Unfortunately, when aneurysms produce symptoms, they can resemble those produced by brain tumors.

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Brain Cancer - Symptoms

The eMedicineHealth physician editors ask:

The symptoms of brain cancer can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

Brain Cancer - Prognosis

The eMedicineHealth physician editors ask:

What is the prognosis for your brain cancer?

Brain cancer symptoms include headache, weakness, seizures, clumsiness, and difficulty walking.

Questions to Ask Your Doctor Before a Biopsy

Medical Author: Melissa Conrad Stöppler, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

A biopsy is a sample of tissue removed by your doctor to make a precise diagnosis. Biopsy procedures can range from a simple sampling of skin under local anesthesiato surgical opening of the chestwall to remove a portion of lung tissue. Biopsies may also be obtained during diagnostic procedures such as endoscopy, colonoscopy, bronchoscopy, and others. Sometimes doctors perform biopsies using a CAT scan or other radiological imaging techniques to help identify the exact area to be sampled and avoid injury to surrounding organs. There are several types of biopsies.

Excisional biopsy. If your doctor finds an area of interest or a suspicious finding (for example, an enlarged nevus, or mole), often an excisional biopsy is performed to remove the area in question in its entirety during the biopsy.

Incisional biopsy. An incisional biopsy refers to removal of only a portion of the area of interest (for example, sampling of a small fragment of tissue from a larger breast lump).

Fine needle biopsy. A fine needle biopsy is used to remove cells or fluid by suctioning through a long, thin needle.

Core needle biopsy. During a core needle biopsy, the doctor inserts a special needle through a skin incision that removes a very thin, cylindrical piece of tissue.

The following questions can help guide your discussions with your doctor concerning a biopsy (print these and take them with you to your doctor's visit):

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Read What Your Physician is Reading on Medscape

Brain, Metastases »

Metastasis to the brain is the most feared complication of systemic cancer and the most common intracranial tumor in adults.

Read More on Medscape Reference »


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