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May 24, 2013

budesonide, Entocort EC Glossary of Terms

The following are health and medical definitions of terms that appear in the budesonide, Entocort EC article.

Abdominal: Relating to the abdomen, the belly, that part of the body that contains all of the structures between the chest and the pelvis. The abdomen is separated anatomically from the chest by the diaphragm, the powerful muscle spanning the body cavity below the lungs.
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Abdominal pain: Pain in the belly. Abdominal pain can be acute or chronic. It may reflect a major problem with one of the organs in the abdomen, such as appendicitis or a perforated intestine, or it may result from a fairly minor problem, such as excess buildup of intestinal gas.

Acne: Localized skin inflammation as a result of overactivity of the oil glands at the base of hair follicles. Acne happens when oil (sebaceous) glands come to life around puberty, when these glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls.
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Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Back pain: Pain felt in the low or upper back. Causes of pain in the low and upper back include conditions affecting the bony spine; discs between the vertebrae; ligaments around the spine and discs; spinal inflammation; spinal cord and nerves; muscles; internal organs of the pelvis, chest, and abdomen; tumors; and the skin.

Bowel: The small and large intestine.

Breast milk: Milk from the breast. Human milk contains a balance of nutrients that closely matches infant requirements for brain development, growth and a healthy immune system. Human milk also contains immunologic agents and other compounds that act against viruses, bacteria, and parasites. Since an infant's immune system is not fully developed until age 2, human milk provides a distinct advantage over formula.
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Chickenpox: A highly infectious viral disease also known medically as varicella -- in many countries, this disease is always called "varicella" -- that causes a blister-like rash, itching, fatigue and fever. The rash crops up first on the face and trunk and can spread over the entire body resulting in 250 to 500 itchy blisters.


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Chronic: In medicine, lasting a long time. A chronic condition is one that lasts 3 months or more. Chronic diseases are in contrast to those that are acute (abrupt, sharp, and brief) or subacute (within the interval between acute and chronic).

Colon: The long, coiled, tubelike organ that removes water from digested food. The remaining material, solid waste called stool, moves through the colon to the rectum and leaves the body through the anus. Also known as large bowel and large intestine.

Corticosteroid: Any of the steroid hormones made by the outer portion (cortex) of the adrenal gland. There are two sets of these hormones: the glucocorticoids, which are produced in reaction to stress and also help in the metabolism of fats, carbohydrates, and proteins; and the mineralocorticoids, which regulate the balance of salt and water within the body.

Cortisol: A metabolite of the primary stress hormone cortisone. Cortisol is an essential factor in the proper metabolism of starches, and it is the major natural glucocorticoid (GC) in humans.

Crohn's disease: A chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. It is named for Burrill Crohn, the American gastroenterologist who first described the disease in 1932.
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Diarrhea: A common condition that involves unusually frequent and liquid bowel movements. The opposite of constipation. There are many infectious and noninfectious causes of diarrhea. Persistent diarrhea is both uncomfortable and dangerous to the health because it can indicate an underlying infection and may mean that the body is not able to absorb some nutrients due to a problem in the bowels. Treatment includes drinking plenty of fluids to prevent dehydration and taking over-the-counter remedies. People with diarrhea that persists for more than a couple days, particularly small children or elderly people, should seek medical attention.

Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction.

Erythromycin: Erythromycin is a common antibiotic for treating bacterial infection. Sold under many brand names, including EES, Erycin and Erythromia.

Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.

FDA: Food and Drug Administration.

Fever: Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.

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Glucocorticoid: A hormone that predominantly affects the metabolism of carbohydrates and, to a lesser extent, fats and proteins (and has other effects). Glucocorticoids are made in the outside portion (the cortex) of the adrenal gland and chemically classed as steroids. Cortisol is the major natural glucocorticoid. The term glucocorticoid also applies to equivalent hormones synthesized in the laboratory.

Headache: A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs. Many hormones are secreted by special glands, such as thyroid hormone produced by the thyroid gland. Hormones are essential for every activity of life, including the processes of digestion, metabolism, growth, reproduction, and mood control. Many hormones, such as neurotransmitters, are active in more than one physical process.

Ileum: Part of the small intestine beyond the jejunum and before the large intestine (colon).

Immune: Protected against infection, usually by the presence of antibodies.

Immune response: Any reaction by the immune system. For example, poison ivy can cause an immune response in the skin characterized by inflammation with tiny blisters, and itching. Also, a flu shot is designed to produce an immune response by stimulating the production of antibodies against the flu virus.

Infant: A young baby, from birth to 12 months of age.

Infection: The invasion and multiplication of microorganisms such as bacteria, viruses, and parasites that are not normally present within the body. An infection may cause no symptoms and be subclinical, or it may cause symptoms and be clinically apparent. An infection may remain localized, or it may spread through the blood or lymphatic vessels to become systemic (bodywide). Microorganisms that live naturally in the body are not considered infections. For example, bacteria that normally live within the mouth and intestine are not infections.

Inflammation: A localized reaction that produces redness, warmth, swelling, and pain as a result of infection, irritation, or injury. Inflammation can be external or internal.

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Insomnia: The perception or complaint of inadequate or poor-quality sleep due to a number of factors, such as difficulty falling asleep, waking up frequently during the night with difficulty returning to sleep, waking up too early in the morning, or unrefreshing sleep. Insomnia is not defined by the number of hours of sleep a person gets or how long it takes to fall asleep; it is a measure of satisfaction with sleep. Individuals vary normally in their need for and their satisfaction with sleep. Insomnia may cause problems during the day, such as tiredness, a lack of energy, difficulty concentrating, and irritability.

Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.

Liver: The largest solid organ in the body, situated in the upper part of the abdomen on the right side. The liver has a multitude of important and complex functions, including to manufacture proteins, including albumin (to help maintain the volume of blood) and blood clotting factors; to synthesize, store, and process fats, including fatty acids (used for energy) and cholesterol; to metabolize and store carbohydrates (used as the source for the sugar in blood); to form and secrete bile that contains bile acids to aid in the intestinal absorption of fats and the fat-soluble vitamins A, D, E, and K; to eliminate, by metabolizing or secreting, the potentially harmful biochemical products produced by the body, such as bilirubin, from the breakdown of old red blood cells and ammonia from the breakdown of proteins; and to detoxify, by metabolizing and/or secreting, drugs, alcohol, and environmental toxins.

Measles: An acute and highly contagious viral disease characterized by fever, runny nose, cough, red eyes, and a spreading skin rash. Measles, also known as rubeola, is a potentially disastrous disease. It can be complicated by ear infections, pneumonia, encephalitis (which can cause convulsions, mental retardation, and even death), the sudden onset of low blood platelet levels with severe bleeding (acute thrombocytopenic purpura), or a chronic brain disease that occurs months to years after an attack of measles (subacute sclerosing panencephalitis).
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Nausea: Stomach queasiness, the urge to vomit. Nausea can be brought on by many causes, including systemic illnesses (such as influenza), medications, pain, and inner ear disease.

Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Potassium: The major positive ion (cation) found inside cells. The chemical notation for potassium is K+. The proper level of potassium is essential for normal cell function. An abnormal increase in potassium (hyperkalemia) or decrease in potassium (hypokalemia) can profoundly affect the nervous system and heart, and when extreme, can be fatal. The normal blood potassium level is 3.5'5.0 milliEquivalents/liter (mEq/L), or 3.5 international units.

Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Pregnant: The state of carrying a developing fetus within the body.
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Proximal: Toward the beginning, the nearer of two (or more) items. For example, the proximal end of the femur is part of the hip joint, and the shoulder is proximal to the elbow. The opposite of proximal is distal.
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Rectum: The last 6 to 8 inches of the large intestine. The rectum stores solid waste until it leaves the body through the anus.

Remission: Disappearance of the signs and symptoms of cancer or other disease. A remission can be temporary or permanent.

Respiratory: Having to do with respiration.

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Small intestine: The part of the digestive tract that extends from the stomach to the large intestine.

Steroid: One of a large group of chemical substances classified by a specific carbon structure. Steroids include drugs used to relieve swelling and inflammation, such as prednisone and cortisone; vitamin D; and some sex hormones, such as testosterone and estradiol.

Stress: In a medical or biological context stress is a physical, mental, or emotional factor that causes bodily or mental tension. Stresses can be external (from the environment, psychological, or social situations) or internal (illness, or from a medical procedure). Stress can initiate the "fight or flight" response, a complex reaction of neurologic and endocrinologic systems.
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Viruses: Small living particles that can infect cells and change how the cells function. Infection with a virus can cause a person to develop symptoms. The disease and symptoms that are caused depend on the type of virus and the type of cells that are infected.

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