December 2, 2008

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Bupropion (Wellbutrin)

Bupropion (Wellbutrin, Zyban) Information

Wellbutrin, Wellbutrin SR, Wellbutrin XL, and Zyban are the brand names. Bupropion is the generic name. Wellbutrin is a medication used to treat depression and belongs to the class known as atypical antidepressants. It is typically prescribed for depression when selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs) are not able to be used or are not effective. For information on atypical antidepressants and how they work, see Understanding Antidepressant Medications. Zyban contains the same active ingredient as Wellbutrin, but it has been approved as an aid to the treatment of nicotine dependence (smoking).

Basic medication information for Wellbutrin (NDA #018644) is as follows:

  • Active ingredient: Bupropion hydrochloride


  • Dosage form: Tablet


  • Strength: 75, 100 mg


  • FDA approval: December 30, 1985


  • Company name: GlaxoSmithKline
Basic medication information for Wellbutrin SR (NDA #020358) is as follows:
  • Active ingredient: Bupropion hydrochloride


  • Dosage form: Tablet, sustained release


  • Strength: 100, 150, 200 mg


  • FDA approval: October 4, 1996


  • Company name: GlaxoSmithKline
Basic medication information for Wellbutrin XL (NDA #021515) is as follows:
  • Active ingredient: Bupropion hydrochloride


  • Dosage form: Tablet, extended release


  • Strength: 150, 300 mg


  • FDA approval: August 29, 2003


  • Company name: GlaxoSmithKline

Basic medication information for Zyban (NDA #020711) is as follows:



Next: Why Is Bupropion Used? »

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