Cancer of the Mouth and Throat Glossary of Terms

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).

Adjacent: Lying nearby. Related terms include superjacent, subjacent, and circumjacent. From ad-, near + the Latin jacere, to lie = to lie near.

Anesthesia: Loss of feeling or awareness. A general anesthetic puts the person to sleep. A local anesthetic causes loss of feeling in a part of the body such as a tooth or an area of skin without affecting consciousness. Regional anesthesia numbs a larger part of the body such as a leg or arm, also without affecting consciousness. The term "conduction anesthesia" encompasses both local and regional anesthetic techniques. Many surgical procedures can be done with conduction anesthesia without significant pain. In many situations, such as a C-section, conduction anesthesia is safer and therefore preferable to general anesthesia. However, there are also many types of surgery in which general anesthesia is clearly appropriate.

Aspiration: Removal of a sample of fluid and cells through a needle. Aspiration also refers to the accidental sucking in of food particles or fluids into the lungs.

Benign: Not cancer. Not malignant. A benign tumor does not invade surrounding tissue or spread to other parts of the body. A benign tumor may grow but it stays put (in the same place).
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Betel nut: The nut of the Areca palm tree and an ingredient of betel nut quid, an addictive mix chewed in some Pacific and Asian cultures. Its use is associated with aggressive oral cancers affecting especially the inner lining of the cheeks and lips are the primary tumor sites. Other sites include the tongue, lower lip, tonsil and floor of the mouth.

Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Bladder: Any pouch or other flexible enclosure that can hold liquids or gases but usually refers to the hollow organ in the lower abdomen that stores urine -- the urinary bladder. The kidneys filter waste from the blood and produce urine, which enters the bladder through two tubes called ureters. Urine leaves the bladder through another tube, the urethra. In women, the urethra is a short tube that opens just in front of the vagina. In men, it is longer, passing through the prostate gland and then the penis. Infection of the bladder is called cystitis.

Brachytherapy: Radiation treatment given by placing radioactive material directly in or near the target, which is often a tumor.
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Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.

Bronchi: The large air tubes leading from the trachea to the lungs that convey air to and from the lungs. The bronchi have cartilage as part of their supporting wall structure. The trachea divides to form the right and left main bronchi which, in turn, divide to form the lobar, segmental, and finally the subsegmental bronchi.
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Buccal mucosa: The inner lining of the cheeks and lips.

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Cancer causes: In most individual cases of cancer, the exact cause of cancer is unknown. The causes may include increased genetic susceptibility; environmental insults, such as chemical exposure or smoking cigarettes; lifestyle factors, including diet; damage caused by infectious disease; and many more.
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Cancer symptoms: Abnormal sensations or conditions that persons can notice that are a result of a cancer. It is important to see your doctor for regular checkups and not wait for problems to occur. But you should also know that the following symptoms may be associated with cancer: changes in bowel or bladder habits, a sore that does not heal, unusual bleeding or discharge, thickening or lump in the breast or any other part of the body, indigestion or difficulty swallowing, obvious change in a wart or mole, or nagging cough or hoarseness. These symptoms are not always a sign of cancer. They can also be caused by less serious conditions. Only a doctor can make a diagnosis. It is important to see a doctor if you have any of these symptoms. Don't wait to feel pain. Early cancer often does not cause pain.

Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast, colon, liver, lung, prostate, and stomach.

Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane.
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Cervix: The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.

Chemotherapy: 1. In the original sense, a chemical that binds to and specifically kills microbes or tumor cells. The term chemotherapy was coined in this regard by Paul Ehrlich (1854-1915).
2. In oncology, drug therapy for cancer. Also called "chemo" for short.
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Chewing tobacco: Tobacco that is chewed, not smoked. A form of smokeless tobacco.
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Chin: Medically, the mentum. The lower portion of the face below the lower lip including the prominence of the lower jaw and the line of fusion of the two separate halves of the jawbone (mandible). This line of fusion (called the symphysis menti) encloses a triangular area at tip of the chin (termed the mental protuberance). On each side, below the second premolar tooth, is the mental foramen, an opening for the passage of blood vessels and a nerve that supply the chin.

Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
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CT scan: Computerized tomography scan. Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them into pictures on a screen. CT stands for computerized tomography.
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Diagnosis: 1 The nature of a disease; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies. 3 The identification of any problem. The diagnosis was a plugged IV.
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Diarrhea: A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation. The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Dry mouth: The condition of not having enough saliva to keep the mouth wet. This is due to inadequate function of the salivary glands. Everyone has dry mouth once in a while when they are nervous, upset or under stress. But if someone has a dry mouth most all of the time, it can be uncomfortable and lead to serious health problems.
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Dysplasia: Abnormal in form. From the Greek dys- (bad, disordered, abnormal) and plassein (to form). For example, retinal dysplasia is abnormal formation of the retina during embryonic development.

Ear: The hearing organ. There are three sections of the ear, according to the anatomy textbooks. They are the outer ear (the part we see along the sides of our head behind the temples), the middle ear, and the inner ear. But in terms of function, the ear has four parts: those three and the brain. Hearing thus involves all parts of the ear as well as the auditory cortex of the brain. The external ear helps concentrate the vibrations of air on the ear drum and make it vibrate. These vibrations are transmitted by a chain of little bones in the middle ear to the inner ear. There they stimulate the fibers of the auditory nerve to transmit impulses to the brain.
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Erythroplakia: A reddened patch with a velvety surface found in the mouth.

Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.

External radiation therapy: Radiation therapy using a machine located outside the body to aim high-energy rays at a tumor.

Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Gland: 1. A group of cells that secrete a substance for use in the body. For example, the thyroid gland. 2. A group of cells that removes materials from the circulation. For example, a lymph gland.

Hair loss: Hair loss is the thinning of hair on the scalp. The medical term for hair loss is alopecia. Alopecia can be temporary or permanent. The most common form of hair loss occurs gradually and is referred to as "androgenetic alopecia," meaning that a combination of hormones (androgens are male hormones) and heredity (genetics) is needed to develop the condition. Other types of hair loss include alopecia areata (patches of baldness that usually grow back), telogen effluvium (rapid shedding after childbirth, fever, or sudden weight loss); and traction alopecia (thinning from tight braids or ponytails).
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Hard palate: The bony part of the roof of the mouth. The hard palate is the front of the palate and is in front of the soft palate.

Head and neck cancer: The common carcinomas of the oral cavity, pharynx, and larynx as well as other tumors that affect the head and neck.
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Heartburn: An uncomfortable feeling of burning and warmth occurring in waves rising up behind the breastbone (sternum) toward the neck. It is usually due to gastroesophageal reflux disease (GERD), the rise of stomach acid back up into the esophagus. Heartburn has nothing whatsoever to do with the heart. It is a popular nonmedical term. It is medically called pyrosis.

Hoarseness: Hoarseness is a term referring to abnormal voice changes. Hoarseness may be manifested as a voice that sounds breathy, strained, rough, raspy, or a voice that has higher or lower pitch. There are many causes of hoarseness, including viral laryngitis, vocal cord nodules, laryngeal papillomas, gastroesophageal reflux-related laryngitis, and environmental irritants (such as tobacco smoking). An accumulation of fluid in the vocal cords associated with hoarseness has been termed Reinke's edema. Reinke's edema may occur as a result of cigarette smoking or voice abuse (prolonged or extended talking or shouting). Rarely, hoarseness results from serious conditions such as cancers of the head and neck region.

Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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HPV: See: Human papillomavirus.

Human papillomavirus: HPV. A family of over 100 viruses including those which cause warts and are transmitted by contact. Some types of HPV are associated with tumors of the genital tract including, notably, cancer of the cervix.
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Incidence: The frequency with which something, such as a disease, appears in a particular population or area. In disease epidemiology, the incidence is the number of newly diagnosed cases during a specific time period. The incidence is distinct from the prevalence which refers to the number of cases alive on a certain date.

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Informatics: The application of computers and statistics to the management of information. For example, in the Human Genome Project, informatics has permitted the development and use of methods to search databases quickly, analyze DNA sequence information, and predict protein sequence and structure from DNA sequence data.

Internal radiation therapy: Radiation therapy in which radioactive material is placed in or near a tumor.

Jaw: The bones below the mouth (the mandible) and the bone above the mouth just above the mouth (the maxilla). The word jaw comes from the Anglo-Saxon ceowan meaning to chew.

Laryngoscopy: Examination of the larynx with a mirror (indirect laryngoscopy) or with a laryngoscope (direct laryngoscopy).
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Larynx: The larynx is the portion of the breathing, or respiratory, tract containing the vocal cords which produce vocal sound. It is located between the pharynx and the trachea. The larynx, also called the voice box, is a 2-inch-long, tube-shaped organ in the neck.

Lesion: Pronounced "lee-sion" with the emphasis on the "lee," a lesion can be almost any abnormality involving any tissue or organ due to any disease or any injury.
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Leukoplakia: A white spot or patch on the mucous membranes in the mouth (for instance, inside the cheeks, on the gums or the tongue) that may become cancerous.

Lips: Aside from the lips of the mouth, there are two pairs of lips at the entrance to the vagina. They are the labia majora (the larger outside pair) and the labia minora (the smaller inside pair). Together they form part of the vulva (the female external genitalia).

Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.

Lymph: An almost colorless fluid that travels through vessels called lymphatics in the lymphatic system and carries cells that help fight infection and disease.

Lymph node: Also sometimes referred to as lymph glands, lymph nodes are small rounded or bean-shaped masses of lymphatic tissue surrounded by a capsule of connective tissue. Lymph nodes are located in many places in the lymphatic system throughout the body. Lymph nodes filter the lymphatic fluid and store special cells that can trap cancer cells or bacteria that are traveling through the body in the lymph fluid. The lymph nodes are critical for the body's immune response and are principal sites where many immune reactions are initiated. During a physical examination, doctors often look for swollen lymph nodes in areas where lymph nodes are abundant, including the neck, around the collarbone, the armpit (axilla), and the groin.
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Lymphatic: 1. One of the lymphatics, vessel that convey the lymph fluid. 2. Pertaining to the lymph, lymphoid tissue, or lymphocytes. 3. Lacking energy. Sluggish.
From the Latin lympha (water or water goddess), from the Greek nymphe (nymph).

Lymphoma: Tumor of the lymphoid tissue. Diagnosis is by biopsy. Treatment may be chemotherapy, radiation, surgery, or medication, depending on the age of the patient and type of tumor.

Malignancy: A tumor that is malignant, that is cancerous, that can invade and destroy nearby tissue, and that may spread (metastasize) to other parts of the body.

Malignant: 1. Tending to be severe and become progressively worse, as in malignant hypertension. 2. In regard to a tumor, having the properties of a malignancy that can invade and destroy nearby tissue and that may spread (metastasize) to other parts of the body.
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Metastasis: 1. The process by which cancer spreads from the place at which it first arose as a primary tumor to distant locations in the body.
2. The cancer resulting from the spread of the primary tumor. For example, someone with melanoma may have a metastasis in their brain. And a person with colon cancer may, fortunately, show no metastases.
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Metastasize: The spread from one part of the body to another. When cancer cells metastasize and cause secondary tumors, the cells in the metastatic tumor are like those in the original cancer.

Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.

Minor salivary gland: A small gland which produces saliva. There are numerous minor salivary glands distributed within the mouth and palate.

Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

MRI: Abbreviation and nickname for magnetic resonance imaging. For more information, see: Magnetic Resonance Imaging; Paul C. Lauterbur; Peter Mansfield.

Mucosa: Having to do with a mucous membrane. For example, the oral mucosa.

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."

Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain, jaundice, fever, or bleeding, a physician should be consulted.

Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.

Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.

Node: Literally a knot, a node is a collection of tissue. For example a lymph node, is a collection of lymphoid tissue. A nodule is a small node, a little collection of tissue.

Nose: The external midline projection from the face.
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Nuclear medicine: The branch of medicine concerned with the use of radioisotopes in the diagnosis, management, and treatment of disease. Nuclear medicine uses small amounts of radioactive materials or radiopharmaceuticals, substances that are attracted to specific organs, bones, or tissues. The radiopharmaceuticals used in nuclear medicine emit gamma rays that can be detected externally by special types of cameras: gamma or PET cameras. These cameras work in conjunction with computers used to form images that provide data and information about the area of body being imaged. The amount of radiation from a nuclear medicine procedure is comparable to that received during a diagnostic x-ray.

Nutrition: 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.

Oncologist: A physician who specializes in the diagnosis and treatment of cancer.
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Oncology: The field of medicine devoted to cancer.
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Operation: Although there are many meanings to the word "operation", in medicine it refers to a surgical procedure.
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Oral cancer: Cancer within the mouth.

Oral surgeon: A dentist with special training in surgery of the mouth and jaw.

Oropharynx: The area of the throat that is at the back of the mouth. The oropharynx is in contrast to the nasopharynx, the part of the throat that lies behind the nose.

Otolaryngologist: A physician specialized in diagnosing and treating diseases of the head and neck, especially those involving the ears, nose, and throat (ENT). Also called an ENT, ENT doctor, or ENT physician.

Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
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PA-C: Physician Assistant - Certified.

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Palate: The roof of the mouth. The front portion is bony (hard palate), and the back portion is muscular (soft palate).

Pathologist: A doctor who identifies diseases by studying cells and tissues under a microscope.

Penis: The external male sex organ used to copulate and ejaculate semen and to convey urine outside the body.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.

Pharynx: The hollow tube about 5 inches long that starts behind the nose and ends at the top of the trachea (windpipe) and esophagus (the tube that goes to the stomach).

Physical therapist: A person trained and certified by a state or accrediting body to design and implement physical therapy programs. Physical therapists may work within a hospital or clinic, in a school providing assistance to special education students, or as an independent practitioner.

Plastic surgeon: A surgeon who specializes in reducing scarring or disfigurement that may occur as a result of accidents, birth defects, or treatment for diseases, such as melanoma.
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Precancerous: Pertaining to something that is not yet overtly cancerous, but appears to be on its way to becoming a cancer. Synonymous with premalignant.

Premalignant: Pertaining to tissue that is not yet malignant, but is poised to become malignant. Appropriate clinical and laboratory studies are designed to detect premalignant tissue while it is still in a premalignant stages. A large battery of techniques are generally available to remove or kill the tissue, thereby preventing the development of cancer. The proper treatment method depends on the particular premalignant tissue involved. Following are a few examples of premalignant growths:
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Primary care: The "medical home" for a patient, ideally providing continuity and integration of health care. All family physicians and most pediatricians and internists are in primary care. The aims of primary care are to provide the patient with a broad spectrum of care, both preventive and curative, over a period of time and to coordinate all of the care the patient receives.

Primary care provider: In insurance parlance, a physician chosen by or assigned to a patient, who both provides primary care and acts as a gatekeeper to control access to other medical services.

Prognosis: 1. The expected course of a disease.
2. The patient's chance of recovery.
The prognosis predicts the outcome of a disease and therefore the future for the patient. His prognosis is grim, for example, while hers is good.
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Prosthetics: The art and science of developing artificial replacements for body parts. Depending on the type of prosthesis, prosthetics may be built and fitted/implanted in a hospital (as in the case of an artificial knee joint), or by an outside specialist. Post- mastectomy prosthetics, for example, may be purchased and fitted by specialized lingerie shops.

Prosthodontist: A dentist with special training in making replacements for missing teeth or other structures of the oral cavity to restore the patient's appearance, comfort, and/or health.
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Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.

Radiation oncologist: A specialist in the use of radiation therapy as a treatment for cancer.

Radiation therapy: The use of high-energy rays to damage cancer cells, stopping them from growing and dividing. Like surgery, radiation therapy is a local treatment that affects cancer cells only in the treated area.
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Radioactive: Emitting energy waves due to decaying atomic nuclei. Radioactive substances are used in medicine as tracers for diagnosis, and in treatment to kill cancerous cells.

Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.

Residual: Something left behind. With residual disease, the disease has not been eradicated.

Risk factor: Something that increases a person's chances of developing a disease.

Rule out: A term much used in medicine, meaning to eliminate or exclude something from consideration. The ACB (albumin cobalt binding) test helps rule out a heart attack in the differential diagnosis of severe chest pain.

Salivary gland: One of the glands in the mouth that produce saliva. There are 3 major salivary glands. They are the parotid, submandibular, and sublingual glands. Each of these glands is paired; there is one parotid gland on each side of the head, etc. The parotid glands are located in front of the ears; the submandibular glands are under the mandible (the lower jaw); and the sublingual glands are under the tongue. Most of the mucosal surfaces within the mouth also contain many minor mucus-secreting salivary glands.
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Scan: As a noun, the data or image obtained from the examination of organs or regions of the body by gathering information with a sensing device.
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Smokeless tobacco: Tobacco that is not smoked but used in another form such as chewing tobacco or snuff. Cancers of the oral cavity (mouth, lip, tongue) have been associated with the use of chewing tobacco as well as snuff. The tumors often arise at the site of placement of the tobacco.
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Snuff: Tobacco in the form of a powder that is inhaled into the nose, not smoked.
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Soft palate: The muscular part of the roof of the mouth. The soft palate is directly behind the hard palate. It lacks bone and so is soft.

Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat. 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

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Sore throat: Pain in the throat. Sore throat may be caused by many different causes, including inflammation of the larynx, pharynx, or tonsils.
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Speech therapist: An older term for a speech- language pathologist.

Squamous cell carcinoma: Cancer that begins in squamous cells -- thin, flat cells that look under the microscope like fish scales. Squamous cells are found in the tissue that forms the surface of the skin, the lining of hollow organs of the body, and the passages of the respiratory and digestive tracts. Squamous cell carcinomas may arise in any of these tissues.
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Squamous cells: Flat cells that look like fish scales. The word "squamous" came from the Latin squama meaning "the scale of a fish or serpent."
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Stage: As regards cancer, the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging.

Staging: In regard to cancer, the process of doing examinations and tests to learn the extent of the cancer, especially whether it has metastasized (spread) from its original site to other parts of the body.

Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Sunscreen: A substance that blocks the effect of the sun's harmful rays. Using lotions that contain sunscreens can reduce the risk of skin cancer, including melanoma.

Supportive care: Treatment given to prevent, control, or relieve complications and side effects and to improve the patient's comfort and quality of life.

Surgeon: A physician who treats disease, injury, or deformity by operative or manual methods. A medical doctor specialized in the removal of organs, masses and tumors and in doing other procedures using a knife (scalpel). The definition of a "surgeon" has begun to blur in recent years as surgeons have begun to minimize the cutting, employ new technologies that are "minimally invasive," use scopes, etc.
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Therapy: The treatment of disease.
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Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth, consisting anatomically of the pharynx and larynx. The throat contains the trachea and a portion of the esophagus.

Thyroid: 1. The thyroid gland. Also, pertaining to the thyroid gland. 2. A preparation of the thyroid gland used to treat hypothyroidism. 3. Shaped like a shield. (The thyroid gland was so-named by Thomas Wharton in 1656 because it was shaped like an ancient Greek shield.)
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Thyroid hormone: A chemical substance made by the thyroid gland for export into the bloodstream. The thyroid gland needs iodine to make thyroid hormones. The two most important thyroid hormones are thyroxine (T4) and triiodothyronine (T3).
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Tired: A feeling of a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a sense of weariness and fatigue.
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Tobacco: A South American herb, formally known as Nicotiana tabacum, whose leaves contain 2-8% nicotine and serve as the source of smoking and smokeless tobacco.
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Tongue: The tongue is a strong muscle anchored to the floor of the mouth. It is covered by the lingual membrane which has special areas to detect tastes.
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Tonsils: Small masses of lymphoid tissue at the back of the throat, on either side of the throat.

Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands).
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Ultraviolet radiation: Invisible rays that are part of the energy that comes from the sun. Ultraviolet radiation can burn the skin and cause skin cancer.
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Vagina: The muscular canal extending from the cervix to the outside of the body. It is usually six to seven inches in length, and its walls are lined with mucus membrane. It includes two vaultlike structures, the anterior (front) vaginal fornix and the posterior (rear) vaginal fornix. The cervix protrudes slightly into the vagina, and it is through a tiny hole in the cervix (the os) that sperm make their way toward the internal reproductive organs. The vagina also includes numerous tiny glands that make vaginal secretions.
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Vitamin A: Vitamin A is retinol. Carotene compounds (found, for example, in egg yolk, butter and cream) are gradually converted by the body to vitamin A (retinol). A form of vitamin A called retinal is responsible for transmitting light sensation in the retina of the eye.
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Voice box: The voice box, or larynx, is the portion of the respiratory (breathing) tract containing the vocal cords which produce sound. It is located between the pharynx and the trachea. The larynx, also called the voice box, is a 2-inch-long, tube-shaped organ in the neck.

Vulva: The female external genital organs including the labia majora, labia minora, clitoris, tiny glands called Bartolin's glands, and the entrance to the vagina (the vestibule of the vagina).

Weight loss: Weight loss is a decrease in body weight resulting from either voluntary (diet, exercise) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer, malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis).

X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer. Formerly called a Roentgen ray. 2. An image obtained by means of X-rays.