The following are health and medical definitions of terms that appear in the cilostazol, Pletal article.
Abdominal: Relating to the abdomen, the belly, that part of the body that contains all of the structures between the chest and the pelvis. The abdomen is separated anatomically from the chest by the diaphragm, the powerful muscle spanning the body cavity below the lungs.
Abdominal pain: Pain in the belly. Abdominal pain can be acute or chronic. It may reflect a major problem with one of the organs in the abdomen, such as appendicitis or a perforated intestine, or it may result from a fairly minor problem, such as excess buildup of intestinal gas.
Abnormal: Outside the expected norm, or uncharacteristic of a particular patient.
Absorption: Uptake. For example, intestinal absorption is the uptake of food (or other substances) from the digestive tract.
Breastfeeding: Feeding a child human breast milk. According to the American Academy of Pediatrics, human breast milk is preferred for all infants. This includes even premature and sick babies, with rare exceptions. It is the food least likely to cause allergic reactions; it is inexpensive; it is readily available at any hour of the day or night; babies accept the taste readily; and the antibodies in breast milk can help a baby resist infections.
Claudication: Limping. From the Latin claudicare, which means 'to limp.' The Roman emperor Claudius was so named because he limped, probably because of a birth defect.
Cure: 1. To heal, to make well, to restore to good health. 2. A time without recurrence of a disease so that the risk of recurrence is small.
Diarrhea: A common condition that involves unusually frequent and liquid bowel movements. The opposite of constipation. There are many infectious and noninfectious causes of diarrhea. Persistent diarrhea is both uncomfortable and dangerous to the health because it can indicate an underlying infection and may mean that the body is not able to absorb some nutrients due to a problem in the bowels. Treatment includes drinking plenty of fluids to prevent dehydration and taking over-the-counter remedies. People with diarrhea that persists for more than a couple days, particularly small children or elderly people, should seek medical attention.
Dilating: The widening and opening of an opening, such as the cervix or esophagus. For example, the amount of widening can be described in terms of the number of fingers that could fit in the cervical opening, or it is described in centimeters.
Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo.
Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions, converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction.
Erythromycin: Erythromycin is a common antibiotic for treating bacterial infection. Sold under many brand names, including EES, Erycin and Erythromia.
FDA: Food and Drug Administration.
Gangrene: Tissue death due to loss of adequate blood supply. Sometimes bacteria invade such tissue and accelerate its decay. Dry gangrene is the death of tissue due to vascular insufficiency without bacterial invasion in which the tissue dies, loses sensation and simply dries up, blackens, and shrivels. Dry gangrene eventually requires amputation. Gas gangrene occurs when body tissue is invaded by bacteria that thrive in areas of low oxygen content. These bacteria are called anaerobic bacteria and include the Clostridium family of bacteria. The bacteria generate gas and pus; the tissues swells and can become painful. Wet gangrene requires urgent antibiotic treatment and sometimes surgical drainage.
Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.
Headache: A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
Heart: The muscle that pumps blood received from veins into arteries throughout the body. The heart is positioned in the chest behind the sternum (breastbone); in front of the trachea, esophagus, and aorta; and above the diaphragm. A normal heart is about the size of a closed fist and weighs about 298 grams or 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest, with the balance in the right side of the chest. The heart is composed of specialized cardiac muscle, and it is four-chambered, with a right atrium and ventricle, and an anatomically separate left atrium and ventricle. The blood flows from the systemic veins into the right atrium, thence to the right ventricle, from which it is pumped to the lungs and then returned into the left atrium, thence to the left ventricle, from which it is driven into the systemic arteries. The heart is thus functionally composed of two hearts: the right heart and the left heart. The right heart consists of the right atrium, which receives deoxygenated blood from the body, and the right ventricle, which pumps the deoxygenated blood to the lungs under low pressure; and the left heart, which consists of the left atrium, which receives oxygenated blood from the lung, and the left ventricle, which pumps the oxygenated blood out to the body under high pressure.
Heart failure: Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling (edema), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
Intermittent claudication: An aching, crampy, tired, and sometimes burning pain in the legs that comes and goes -- it typically occurs with walking and goes away with rest -- due to poor circulation of blood in the arteries of the legs. In very severe claudication the pain is also felt ar rest. Intermittent claudication may occur in one or both legs and often continues to worsen over time. However, some people complain only of weakness in the legs when walking or a feeling of "tiredness" in the buttocks. Impotence is an occasional complaint in men.
Leg: In popular usage, the part of the body from the top of the thigh down to the foot, and in medical terminology, the portion of the lower extremity that runs from the knee to the ankle. The leg (in the medical sense) has two bones'the tibia (shinbone) and the fibula'both of which are known as long bones. The larger of the two is the tibia. The fibula runs alongside the tibia.
Nausea: Stomach queasiness, the urge to vomit. Nausea can be brought on by many causes, including systemic illnesses (such as influenza), medications, pain, and inner ear disease.
Nose: The external midline projection from the face. The purpose of the nose is to warm, clean, and humidify the air that a person breathes. In addition, it helps a person to smell and taste. The nose is divided into two passageways by a partition called the septum. Opening to these passageways are the nostrils. Bony projections, called turbinates, protrude into each breathing passage; they help to increase the surface area of the inside of the nose. There are three turbinates on each side of the nose (the inferior, middle, and superior turbinates). The sinuses are four paired air-filled chambers that empty into the nasal cavity.
Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.
Oxygen: The odorless gas that is present in the air and necessary to maintain life. Oxygen may be given in a medical setting, either to reduce the volume of other gases in the blood or as a vehicle for delivering anesthetics in gas form. It can be delivered via nasal tubes, an oxygen mask, or an oxygen tent. Patients with lung disease or damage may need to use portable oxygen devices on a temporary or permanent basis.
Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.
Red blood cells: The blood cells that carry oxygen. Red cells contain hemoglobin and it is the hemoglobin which permits them to transport oxygen (and carbon dioxide). Hemoglobin, aside from being a transport molecule, is a pigment. It gives the cells their red color (and their name).
Respiratory: Having to do with respiration.
Runny nose: The production of extra mucus by the nose. Rhinorrhea is the medical term for this common problem. The nose makes extra mucus whenever something that is in the nose, such as pollen or dust, needs to be removed. Mucus formation is also part of the histamine reaction to allergies and of the body's defenses during respiratory infections.
Stool: The solid matter that is discharged in a bowel movement.
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