Cinchona

Are there any interactions with medications?

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Quinidine
Interaction Rating: Major Do not take this combination.

Cinchona contains quinidine. Taking quinidine along with cinchona can increase the effects and side effects of quinidine and cause heart problems. Do not take cinchona if you are taking quinidine.

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Quinine
Interaction Rating: Major Do not take this combination.

Cinchona contains quinine. Taking quinidine along with cinchona can increase the effects and side effects of quinine and cause heart problems. Do not take cinchona if you are taking quinine.

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Carbamazepine (Tegretol)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down carbamazepine to get rid of it. Cinchona contains quinine. Quinine can cause the body to break down carbamazepine (Tegretol) too quickly. Taking cinchona along with carbamazepine (Tegretol) can decrease the effectiveness of carbamazepine (Tegretol).

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Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Cinchona might slow blood clotting. Taking cinchona along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

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Phenobarbital (Luminal)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Cinchona contains quinine. Quinine might increase how much phenobarbital (Luminal) is in the body. Taking cinchona with phenobarbital might increase the effects and side effects of phenobarbital.

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Antacids
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Antacids are used to decrease stomach acid. Cinchona may increase stomach acid. By increasing stomach acid, cinchona might decrease the effectiveness of antacids.

Some antacids include calcium carbonate (Tums, others), dihydroxyaluminum sodium carbonate (Rolaids, others), magaldrate (Riopan), magnesium sulfate (Bilagog), aluminum hydroxide (Amphojel), and others.

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Medications that decrease stomach acid (H2-blockers)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Cinchona might increase stomach acid. By increasing stomach acid, cinchona might decrease the effectiveness of some medications that decrease stomach acid, called H2-blockers.

Some medications that decrease stomach acid include cimetidine (Tagamet), ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid).

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Medications that decrease stomach acid (Proton pump inhibitors)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Cinchona might increase stomach acid. By increasing stomach acid, cinchona might decrease the effectiveness of medications that are used to decrease stomach acid, called proton pump inhibitors.

Some medications that decrease stomach acid include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium).

Dosing considerations for Cinchona.

The appropriate dose of cinchona depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for cinchona. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.