The National Institute of Neurological Disorders and Stroke (NINDS), a part of the National Institutes of Health, is the leading U.S. federal government agency supporting research on brain and nervous system disorders. It provides the public with educational materials and information about these disorders.

The American Headache Society Committee for Headache Education (ACHE) is a nonprofit partnership between health professionals and headache sufferers. ACHE provides resources and tools to health care professionals to help them help their headache patients. This website has many educational resources for doctors, patients, families, schools, and employers. Resources include newsletters, articles on headaches, tools for both patients and doctors, and lists of certified headache doctors.

The National Headache Foundation is a nonprofit organization dedicated to three major goals: educating the public that headaches are serious disorders and that sufferers need understanding and continuity of care; promoting research into potential headache causes and treatments; and serving as an information resource for sufferers, their families, and doctors who treat them. The NHF can provide lists of local doctors specializing in headache treatment. It also has a monthly newsletter and many pamphlets on a variety of topics related to the different headache syndromes.

The National Pain Foundation (NPF) promotes the recovery of persons in pain. NPF's website provides information and resources in an interactive way that encourages patients to take an active role in managing their chronic pain. The My Pain section of the website includes a Personal Inventory section to help pain patients identify the information they need to manage their pain.

The NPF has information about pain conditions such as arthritis, back and neck pain, and cancer pain. The NPF addresses the many approaches to pain management, such as medicines, injections, surgery, acupuncture, biofeedback, chiropractic, and physical therapy. The NPF also provides support for the special needs of children in pain and information about psychological factors related to pain. The website also provides information on clinical trials that are studying pain management and treatment.