Few topics generate anxiety in new parents as the possibility that their infant may have colic. First described in biblical times, Dr. Morris A. Wessel defined colic in 1954 as "excessive" crying lasting more than three hours a day, more than three days per week, and for more than three consecutive weeks. These children are otherwise well and their crying is not due to either pain or hunger. This inordinate crying starts about 2 weeks of age, hits a maximum in intensity at about 6-8 weeks of age, and then gradually diminishes with resolution by 16 weeks of age. Many developmental specialists point out that premature babies will follow this same pattern and also start their colicky experience about two weeks after their due date (regardless of actual date of birth). Studies have indicated that approximately 20% of healthy newborns may experience colic.