Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.
Most colorectal cancers arise from adenomatous
polyps-clusters of abnormal cells in the glands covering the inner wall of the colon. Over time, these abnormal growths enlarge and ultimately degenerate to become adenocarcinomas.
People with any of several conditions known as adenomatous polyposis syndromes have a greater-than-normal risk of colorectal cancer.
In these conditions, numerous adenomatous polyps
develop in the colon, ultimately leading to colon cancer.
The cancer usually occurs before age 40 years.
Adenomatous polyposis syndromes tend to run in families. Such cases are referred to as familial adenomatous polyposis (FAP). Celecoxib (Celebrex) has been FDA approved for FAP.
After 6 months, celecoxib reduced the mean number of rectal and colon polyps by 28% compared to placebo (sugar pill) 5%.
The risk of
colon cancer increases 2-3 times for people with a first-degree relative (parent
or sibling) with colon cancer. The risk increases more if you have more than one affected family member, especially if the cancer was diagnosed at a young age.
Other factors that may affect your risk of developing a colon cancer:
Diet: Whether diet plays a role in developing colon
cancer remains under debate. The belief that a high-fiber, low-fat diet could
help prevent colon cancer has been questioned. Studies do indicate that
exercise and a diet rich in fruits and vegetables can help prevent colon
Obesity: Obesity has
been identified as a risk factor for colon cancer.
Smoking: Cigarette smoking
has been definitely linked to a higher risk for colon cancer.