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With early diagnosis and treatment, about 75% of people with cryptococcosis will have a good or excellent prognosis because the infection will be stopped. Those who are diagnosed late in the infectious process or who are immunosuppressed have a fair to poor prognosis and may have a mortality (death) rate as high as 30%. Those who survive have a relapse or reactivation rate as high as 25% while others often have long-term (years) or lifelong requirements for suppression treatment with antifungal drugs.
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