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May 19, 2013
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Cryptococcosis (cont.)

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Cryptococcosis Signs and Symptoms

Several researchers suggest that the first sign that cryptococcosis is in an area is the increased diagnosis of the disease in animals, especially domestic pets. Although the animals do not pass the disease to humans, their disease indicates a likely chance of exposure of humans to Cryptococcus. People with lung or CNS (brain or central nervous system) problems who have visited or inhabited areas where animals have acquired the infection should be tested for the disease.

The majority of symptoms of cryptococcosis occur in the lungs, the brain, or both. The following is a list of the major symptoms:

  • Fever


  • Malaise


  • Pleuritic chest pain (sharp pain that occurs over the area of inflammation and increases with breathing movements)


  • Cough, usually nonproductive


  • Hemoptysis (bloody or blood tinged sputum)


  • Headache


  • Vision changes (blurry or double vision, photophobia)


  • Nausea and vomiting


  • Mental status changes (lethargy, confusion)


  • Meningitis


  • Seizures


  • Coma

About 10%-15% may develop skin changes (rash, pustules, nodules, ulcers).

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