Cushing Syndrome (cont.)
IN THIS ARTICLE
The outlook is favorable if surgery is curative.
The rare adrenal carcinomas are associated with a 5-year survival rate of 30% or less.
Two catastrophic medical crises that occur in corticosteroid excess states are perforated viscera (such as the stomach, duodenum, small intestine) and opportunistic saprophytic or fungal infections.
Exposure to excess corticosteroid results in multiple medical problems, including high blood pressure, obesity, osteoporosis, fractures, impaired immune function, impaired wound healing, glucose intolerance, and psychosis.
Exogenous steroids suppress the hypothalamic-pituitary-adrenal axis, with full recovery taking as long as a year after stopping corticosteroid medication. Thus, persons who are on or who have taken steroids are at risk for developing an adrenal crisis (a life-threatening condition caused by insufficient corticosteroid).
Medically Reviewed by a Doctor on 11/30/2015
George P Chrousos, MD, FAAP, MACP, MACE
Shehnaz Shaikh, MD
Arthur B Chausmer, MD, PhD, FACP, FACE, FACN, CNS
Mary L Windle, PharmD
George T Griffing, MD
Must Read Articles Related to Cushing Syndrome
Patient Comments & Reviews
The eMedicineHealth doctors ask about Cushing Syndrome:
Cushing Syndrome - Experience
Please describe your experience with Cushing's syndrome.
Cushing Syndrome - Symptoms
What were the symptoms of your Cushing's syndrome?
Cushing Syndrome - Medical Treatment
What was the treatment for your medical treatment?
Women's Health Resources
- Early Puberty? When to See a Doctor
- What Is Inherited Lipodystrophy?
- Are We Close to a Cure for Cancer?