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February 8, 2012
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Dementia Due to HIV Infection

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Dementia Due to HIV Infection Overview

Decline in mental processes is a common complication of HIV infection (and many other conditions).

  • Although the specific symptoms vary from person to person, they may be part of a single disorder known as AIDS dementia complex, or ADC. Other names for ADC are HIV-associated dementia and HIV/AIDS encephalopathy.

  • Common symptoms include decline in thinking, or “cognitive,” functions such as memory, reasoning, judgment, concentration, and problem solving.

  • Other common symptoms are changes in personality and behavior, speech problems, and motor (movement) problems such as clumsiness and poor balance.

  • When these symptoms are severe enough to interfere with everyday activity, a diagnosis of dementia may be warranted. 

AIDS dementia complex typically occurs as CD4+ count falls to less than 200 cells/microliter. It may be the first sign of AIDS. With the advent of highly active antiretroviral therapy (HAART), the frequency of ADC has declined from 30-60% of people infected with HIV to less than 20%. HAART may not only prevent or delay the onset of AIDS dementia complex in people with HIV infection, it can also improve mental function in people who already have ADC.

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Dementia Due to HIV Infection

Dementia Overview

Dementia is a decline of reasoning, memory, and other mental abilities (the cognitive functions). This decline eventually impairs the ability to carry out everyday activities such as driving; household chores; and even personal care such as bathing, dressing, and feeding (often called activities of daily living, or ADLs).

  • Dementia is most common in elderly people; it used to be called senility and was considered a normal part of aging.

  • We now know that dementia is not a normal part of aging but is caused by a number of underlying medical conditions that can occur in both elderly and younger persons.

  • In some cases, dementia can be reversed with proper medical treatment. In others, it is permanent and usually gets worse over time.

About 4-5 million people in the United States have some degree of dementia, and that number will increase over the next few decades with the aging of ...

Read the Dementia article »


Read What Your Physician is Reading on Medscape

Dementia Due to HIV Disease »

Physicians frequently encounter neurologic and psychiatric complications in patients with human immunodeficiency virus (HIV) infection.

Read More on Medscape Reference »

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