Dementia Due to HIV Infection (cont.)
CT scan of the brain of a patient with AIDS dementia complex (ADC) shows diffuse atrophy (loss of tissue) and ventricular enlargement and attenuation (dark areas) around the ventricles in the white matter.
T2-weighted MRI shows ventricular enlargement and large areas of hyperintense signal in the subcortical white matter of both frontal lobes.
Photomicrograph from a patient with AIDS dementia complex (ADC) shows perivascular and parenchymal infiltrates of lymphocytes and macrophages. These often form microglial nodules. Contributed by Dr. Beth Levy, Saint Louis University School of Medicine, St. Louis, Mo.
Photomicrograph from patient with AIDS dementia complex (ADC) illustrates the intense astrogliosis (scarring) that is characteristic of HIV encephalitis. Contributed by Dr. Beth Levy, Saint Louis University School of Medicine, St. Louis, Mo.
Multinucleated giant cells, as shown here, are a hallmark of HIV encephalitis and harbor the virus. Contributed by Dr. Beth Levy, Saint Louis University Health Sciences Center, St. Louis, Mo.
Medically reviewed by Jon Glass, MD; American board of Psychiatry and NeurologyLast Editorial Review: 8/5/2014
Florian P Thomas, MD, MA, PhD
Nestor Galvez-Jimenez, MD
Francisco Talavera, PharmD, PhD
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