Dementia With Lewy Bodies Glossary of Medical Terms

These are medical definitions of medical terms from the MedTerms.com medical dictionary that appear in the Dementia With Lewy Bodies article.

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
See the entire definition of Abnormal

Acetylcholine: A key chemical in neurons (nerve cells) that acts as a neurotransmitter and carries information across the synaptic cleft , the space between two nerve cells. Abbreviated ACh.
See the entire definition of Acetylcholine

Acetylcholinesterase: An enzyme that breaks down the neurotransmitter acetylcholine at the synaptic cleft (the space between two nerve cells) so the next nerve impulse can be transmitted across the synaptic gap. Pesticides of the organophosphate and carbamate types act to paralyze and kill insects by inhibiting their acetylcholinesterase. Abbreviated AChE.
See the entire definition of Acetylcholinesterase

Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
See the entire definition of Aging

Alpha-synuclein: One in a family of structurally related proteins that are prominently expressed in the central nervous system . Aggregated alpha-synuclein proteins form brain lesions that are hallmarks of some neurodegenerative diseases (synucleinopathies). The gene for alpha-synuclein, which is called SNCA, is on chromosome 4q21. One form of hereditary Parkinson disease is due to mutations in SNCA. Another form of hereditary Parkinson disease is due to a triplication of SNCA. See also: Parkinson disease gene .
See the entire definition of Alpha-synuclein

Alzheimer disease: See: Alzheimer's disease .
See the entire definition of Alzheimer disease

Antidepressant: Anything, and especially a drug, used to prevent or treat depression.
See the entire definition of Antidepressant

Antidepressants : Anything, and especially a drug, used to prevent or treat depression .
See the entire definition of Antidepressants

Antioxidant: Any substance that reduces oxidative damage (damage due to oxygen ) such as that caused by free radicals. Free radicals are highly reactive chemicals that attack molecules by capturing electrons and thus modifying chemical structures.
See the entire definition of Antioxidant

Antipsychotic: A medication (or another measure) that is believed to be effective in the treatment of psychosis . For example, aripiprazole (Abilify) is an antipsychotic medication used to treat schizophrenia .
See the entire definition of Antipsychotic

Atrophy: Wasting away or diminution. Muscle atrophy is wasting of muscle, decrease in muscle mass.
See the entire definition of Atrophy

Atypical: Not typical, not usual, not normal, abnormal. Atypical is often used to refer to the appearance of precancerous or cancerous cells.
See the entire definition of Atypical

Autopsy : A postmortem examination. Also called a necropsy .
See the entire definition of Autopsy

Baseline: 1. Information gathered at the beginning of a study from which variations found in the study are measured.
2. A known value or quantity with which an unknown is compared when measured or assessed.
3. The initial time point in a clinical trial, just before a participant starts to receive the experimental treatment which is being tested. At this reference point, measurable values such as CD4 count are recorded. Safety and efficacy of a drug are often determined by monitoring changes from the baseline values.
See the entire definition of Baseline

Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
See the entire definition of Brain

^ Back to Top

Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
See the entire definition of Cell

Cognition: The process of knowing and, more precisely, the process of being aware, knowing, thinking, learning and judging. The study of cognition touches on the fields of psychology, linguistics, computer science, neuroscience, mathematics, ethology and philosophy.
See the entire definition of Cognition

Cognitive: Pertaining to cognition , the process of knowing and, more precisely, the process of being aware, knowing, thinking, learning and judging. The study of cognition touches on the fields of psychology , linguistics, computer science, neuroscience , mathematics, ethology and philosophy.
See the entire definition of Cognitive

Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
See the entire definition of Complication

Constipation: Infrequent (and frequently incomplete) bowel movements. The opposite of diarrhea , constipation is commonly caused by irritable bowel syndrome, diverticulosis , and medications (constipation can paradoxically be caused by overuse of laxatives). Colon cancer can narrow the colon and thereby cause constipation. The large bowel (colon) can be visualized by barium enema x-rays, sigmoidoscopy, and colonoscopy. Barring a condition such as cancer, high-fiber diets can frequently relieve the constipation.
See the entire definition of Constipation

CT scan: Computerized tomography scan. Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them into pictures on a screen. CT stands for computerized tomography.
See the entire definition of CT scan

Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma .
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
See the entire definition of Cure

Dementia : Significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning.
See the entire definition of Dementia

Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
See the entire definition of Depression

Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
See the entire definition of Diagnosis

Dopamine: An important neurotransmitter (messenger) in the brain.
See the entire definition of Dopamine

EEG: Electroencephalogram, e technique for studying the electrical current within the brain. Electrodes are attached to the scalp. Wires attach these electrodes to a machine which records the electrical impulses. The results are either printed out or displayed on a computer screen. Electroencephalogram is abbreviated EEG.
See the entire definition of EEG

Gait: A manner of walking. Observation of the gait can provide clues to a number of diagnoses including Parkinson disease, cerebral palsy , congenital dislocation of the hip, and stroke .
See the entire definition of Gait

Indicate: In medicine, to make a treatment or procedure advisable because of a particular condition or circumstance. For example, certain medications are indicated for the treatment of hypertension during pregnancy while others are contraindicated .
See the entire definition of Indicate

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

^ Back to Top

Lab test: A test that is done in the laboratory where the appropriate equipment, supplies, and certified expertise are available.
See the entire definition of Lab test

Lumbar: Referring to the 5 lumbar vertebrae which are situated below the thoracic vertebrae and above the sacral vertebrae in the spinal column. The 5 lumbar vertebrae are represented by the symbols L1 through L5. There are correspondingly 5 lumbar nerves.
See the entire definition of Lumbar

Lumbar puncture: A lumbar puncture or "LP" is a procedure whereby spinal fluid is removed from the spinal canal for the purpose of diagnostic testing. It is particularly helpful in the diagnosis of inflammatory diseases of the central nervous system, especially infections, such as meningitis. It can also provide clues to the diagnosis of stroke , spinal cord tumor and cancer in the central nervous system.
See the entire definition of Lumbar puncture

Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.
See the entire definition of Lungs

Malnutrition: A term used to refer to any condition in which the body does not receive enough nutrients for proper function. Malnutrition may range from mild to severe and life-threatening. It can be a result of starvation, in which a person has an inadequate intake of calories, or it may be related to a deficiency of one particular nutrient (for example, vitamin C deficiency). Malnutrition can also occur because a person can not properly digest or absorb nutrients from the food they consume, as may occur with certain medical conditions. Malnutrition remains a significant global problem, especially in developing countries.
See the entire definition of Malnutrition

MAOI: Monoamine oxidase inhibitor. One of a potent class of medications used to treat depression .
See the entire definition of MAOI

Marker: A piece of DNA that lies on a chromosome so close to a gene that the marker and the gene are inherited together. A marker is thus an identifiable heritable spot on a chromosome. A marker can be an expressed region of DNA (a gene) or a segment of DNA with no known coding function. All that matters is that the marker can be detected and trailed.
See the entire definition of Marker

Medical history: 1. In clinical medicine, the patient's past and present which may contain clues bearing on their health past, present, and future. The medical history, being an account of all medical events and problems a person has experienced, including psychiatric illness, is especially helpful when a differential diagnosis is needed.
2. The history of medicine.
See the entire definition of Medical history

Memory: 1. The ability to recover information about past events or knowledge. 2. The process of recovering information about past events or knowledge. 3. Cognitive reconstruction. The brain engages in a remarkable reshuffling process in an attempt to extract what is general and what is particular about each passing moment.
See the entire definition of Memory

Metabolic: Relating to metabolism, the whole range of biochemical processes that occur within us (or any living organism). Metabolism consists of anabolism (the buildup of substances) and catabolism (the breakdown of substances).
See the entire definition of Metabolic

Motor: In medicine, having to do with the movement of a part of the body. Something that produces motion or refers to motion. For example, a motor neuron is a nerve cell that conveys an impulse to a muscle causing it to contract. The term "motor" today is also applied to a nerve that signals a gland to secrete. Motor is as opposed to sensory.
See the entire definition of Motor

MRI: Abbreviation and nickname for magnetic resonance imaging . For more information, see: Magnetic Resonance Imaging ; Paul C. Lauterbur ; Peter Mansfield .
See the entire definition of MRI

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
See the entire definition of Muscle

Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system .
See the entire definition of Nerve

Neuroleptic: A term that refers to the effects of antipsychotic drugs on a patient, especially on his or her cognition and behavior.
See the entire definition of Neuroleptic

^ Back to Top

Neurological: Having to do with the nerves or the nervous system.
See the entire definition of Neurological

Neurology: The medical specialty concerned with the diagnosis and treatment of disorders of the nervous system -- the brain, the spinal cord, and the nerves.
See the entire definition of Neurology

Neurotransmitter: A chemical that is released from a nerve cell which thereby transmits an impulse from a nerve cell to another nerve, muscle, organ, or other tissue. A neurotransmitter is a messenger of neurologic information from one cell to another.
See the entire definition of Neurotransmitter

NINDS: Stands for the National Institute of Neurological Disorders and Stroke, one of the National Institutes of Health in the U.S., whose mission is to "support and conduct research and research training on the normal structure and function of the nervous system and on the causes, prevention, diagnosis, and treatment of more than 600 nervous system disorders including stroke , epilepsy , multiple sclerosis , Parkinson's disease, head and spinal cord injury, Alzheimer's disease, and brain tumors."
See the entire definition of NINDS

Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast .
See the entire definition of Nursing

Nursing home: A residential facility for persons with chronic illness or disability, particularly older people who have mobility and eating problems. Also called a convalescent home, long-term care facility.
See the entire definition of Nursing home

Nutrition : 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.
See the entire definition of Nutrition

Parkinson disease : A slowly progressive neurologic disease characterized by a fixed inexpressive face, a tremor at rest, slowing of voluntary movements, a gait with short accelerating steps, peculiar posture and muscle weakness, caused by degeneration of an area of the brain called the basal ganglia , and by low production of the neurotransmitter dopamine . Most patients are over 50, but at least 10 percent are under 40. Also known as paralysis agitans and shaking palsy.
See the entire definition of Parkinson disease

Parkinson's disease: See: Parkinson disease .
See the entire definition of Parkinson's disease

Parkinsonism: 1. Parkinson disease .
2. A syndrome similar to Parkinson disease, for example, as a side effect of an antipsychotic drug.
See the entire definition of Parkinsonism

Pathology: The study of disease. Pathology has been defined as "that branch of medicine which treats of the essential nature of disease." The word "pathology" comes from the Greek words "pathos" meaning "disease" and "logos" meaning "a treatise" = a treatise of disease. The word "pathology" is sometimes misused to mean disease as, for example, "he didn't find any pathology" (meaning he found no evidence of disease). A medical doctor that specializes in pathology is called a pathologist. Pathologists are experts at interpreting microscopic views of body tissues.
See the entire definition of Pathology

Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
See the entire definition of Pharmacy

Pneumonia: Inflammation of one or both lungs with consolidation. Pneumonia is frequently but not always due to infection. The infection may be bacterial, viral, fungal or parasitic. Symptoms may include fever, chills, cough with sputum production, chest pain, and shortness of breath.
See the entire definition of Pneumonia

Precursor: Forerunner. That which precedes or is derived from an available source.
See the entire definition of Precursor

Progressive: Increasing in scope or severity. Advancing. Going forward. In medicine, a disease that is progressive is going from bad to worse.
See the entire definition of Progressive

^ Back to Top

Protein: A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
See the entire definition of Protein

Proteins: Large molecules composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
See the entire definition of Proteins

Quality of life: An important consideration in medical care, quality of life refers to the patient's ability to enjoy normal life activities. Some medical treatments can seriously impair quality of life without providing appreciable benefit, while others greatly enhance quality of life.
See the entire definition of Quality of life

Recent memory: Short-term memory. Also called working memory.
See the entire definition of Recent memory

Referral: The recommendation of a medical or paramedical professional. If you get a referral to ophthalmology, for example, you are being sent to the eye doctor. In HMOs and other managed care schemes, a referral is usually necessary to see any practitioner or specialist other than your primary care physician (PCP), if you want the service to be covered. The referral is obtained from your PCP, who may require a telephone or office consultation first.
See the entire definition of Referral

Reuptake: The reabsorption of a secreted substance by the cell that originally produced and secreted it. The process of reuptake, for example, affects serotonin.
See the entire definition of Reuptake

Rule out: A term much used in medicine, meaning to eliminate or exclude something from consideration. The ACB (albumin cobalt binding) test helps rule out a heart attack in the differential diagnosis of severe chest pain.
See the entire definition of Rule out

Scan: As a noun, the data or image obtained from the examination of organs or regions of the body by gathering information with a sensing device.
See the entire definition of Scan

Senile: 1. Pertaining to old age. 2. Pertaining to the physical decline associated with old age. 3. Pertaining to the mental decline once associated with old age but now known to be due to dementia , such as Alzheimer's disease or cerebral atherosclerosis . "The road to senility is paved with plaques." (Paul F. Wehrle, MD [1921-2004] pediatrician and vaccine researcher)
See the entire definition of Senile

Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
See the entire definition of Sensitivity

Serotonin: A hormone , also called 5-hydroxytryptamine , in the pineal gland , blood platelets, the digestive tract, and the brain. Serotonin acts both as a chemical messenger that transmits nerve signals between nerve cells and that causes blood vessels to narrow.
See the entire definition of Serotonin

Spinal tap: Also known as a lumbar puncture or "LP", a spinal tap is a procedure whereby spinal fluid is removed from the spinal canal for the purpose of diagnostic testing. It is particularly helpful in the diagnosis of inflammatory diseases of the central nervous system, especially infections, such as meningitis. It can also provide clues to the diagnosis of stroke , spinal cord tumor and cancer in the central nervous system.
See the entire definition of Spinal Tap

Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
See the entire definition of Stomach

Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
See the entire definition of Stress

Stroke: The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
See the entire definition of Stroke

^ Back to Top

Therapy: The treatment of disease .
See the entire definition of Therapy

Thyroid: 1. The thyroid gland . Also, pertaining to the thyroid gland. 2. A preparation of the thyroid gland used to treat hypothyroidism . 3. Shaped like a shield. (The thyroid gland was so-named by Thomas Wharton in 1656 because it was shaped like an ancient Greek shield.)
See the entire definition of Thyroid

Tremor: Any abnormal repetitive shaking movement of the body. Tremors have many causes and can be inherited, be related to illnesses such as thyroid disease , or caused by fever , hypothermia, drugs or fear.
See the entire definition of Tremor

Tricyclic antidepressants (TCAs): One of a class of medications used to treat depression . The tricyclic antidepressants (TCAs) are also used for some forms of anxiety, fibromyalgia , and the control of chronic pain.
See the entire definition of Tricyclic antidepressants

Vascular: Relating to the blood vessels of the body. The blood vessels of the body, as a group, are referred to as the vascular system.
See the entire definition of Vascular

Vascular dementia: A common form of dementia in older persons that is due to cerebrovascular disease, usually with stepwise deterioration from a series of small strokes and a patchy distribution of neurologic deficits affecting some functions and not others. Risk factors include high blood pressure , an unsteady way of walking, and advanced age. Symptoms include confusion, problems with recent memory, wandering or getting lost in familiar places, loss of bladder or bowel control (incontinence), emotional problems such as laughing or crying inappropriately, difficulty following instructions, and problems handling money. The damage is typically so slight that the change is noticeable only as a series of small steps. However, over time, as more small blood vessels in the brain are blocked, there is noticeable gradual mental decline. Vascular dementia commonly begins between the ages of 60 and 75 and affects men more often than women. Also known as multi-infarct dementia. See also CADASIL .
See the entire definition of Vascular dementia

Vitamin E: Alpha-tocopherol, an antioxidant vitamin which binds oxygen free radicals that can cause tissue damage. Deficiency of vitamin E can lead to anemia . Vitamin E may play a possible role in preventing heart disease and cancer of the lung and prostate .
See the entire definition of Vitamin E

^ Back to Top