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May 26, 2013
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Diabetes Mellitus

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Diabetes Overview

Diabetes mellitus (DM) is a set of related diseases in which the body cannot regulate the amount of sugar (specifically, glucose) in the blood.

The blood delivers glucose to provide the body with energy to perform all of a person's daily activities.

  • The liver converts the food a person eats into glucose. The glucose is then released into the bloodstream.
  • In a healthy person, the blood glucose level is regulated by several hormones, primarily insulin. Insulin is produced by the pancreas, a small organ between the stomach and liver. The pancreas also makes other important enzymes released directly into the gut that helps digest food.
  • Insulin allows glucose to move out of the blood into cells throughout the body where it is used for fuel.
  • People with diabetes either do not produce enough insulin (type 1 diabetes) or cannot use insulin properly (type 2 diabetes), or both (which occurs with several forms of diabetes).
  • In diabetes, glucose in the blood cannot move efficiently into cells, so blood glucose levels remain high. This not only starves all the cells that need the glucose for fuel, but also harms certain organs and tissues exposed to the high glucose levels.
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Viewer Comments & Reviews

Diabetes - Symptoms

The eMedicineHealth physician editors ask:

The symptoms of diabetes can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

Diabetes Treatment - Effective Treatments

The eMedicineHealth physician editors ask:

Please describe what treatments have been effective for your diabetes.

Diabetes + Smoking = Trouble

Medical Author: Ruchi Mathur, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

I can summarize this little article in one quick sentence: Smoking is bad. In the general population, and particularly in patients with diabetes...Smoking is bad.

Cigarette smoking is the leading cause if avoidable death in the United States, and accounts for almost 500,000 deaths a year. Smoking plays a role in one out of every five deaths in the United States per year. Smoking is indeed bad.

Where the health of diabetic smokers is concerned, the statistics are even worse. There is an increased risk of premature death and the development of heart disease in patients who have diabetes and continue to smoke. There is also evidence that links cigarette smoking with microvascular disease (kidney and eye damage) in diabetes. Additionally, there is data that shows that smoking may actually play a role in the development of type 2 diabetes. Smoking is bad.

Diabetes

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Read What Your Physician is Reading on Medscape

Diabetes Mellitus, Type 2 »

Type 2 diabetes mellitus is a group of disorders characterized by hyperglycemia and associated with microvascular (ie, retinal, renal, possibly neuropathic), macrovascular (ie, coronary, peripheral vascular), and neuropathic (ie, autonomic, peripheral) complications.

Read More on Medscape Reference »


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