The following are health and medical definitions of terms that appear in the digoxin, Lanoxin article.
Abdominal: Relating to the abdomen, the belly, that part of the body that contains all of the structures between the chest and the pelvis. The abdomen is separated anatomically from the chest by the diaphragm, the powerful muscle spanning the body cavity below the lungs.
Abdominal pain: Pain in the belly. Abdominal pain can be acute or chronic. It may reflect a major problem with one of the organs in the abdomen, such as appendicitis or a perforated intestine, or it may result from a fairly minor problem, such as excess buildup of intestinal gas.
Abnormal: Outside the expected norm, or uncharacteristic of a particular patient.
Alcoholism: Physical dependence on alcohol to the extent that stopping alcohol use would bring on withdrawal symptoms. In popular and therapeutic parlance, the term may also be used to refer to ingrained drinking habits that cause health or social problems. Treatment requires first ending the physical dependence and then making lifestyle changes that help the individual avoid relapse. In some cases, medication and hospitalization are necessary. Alcohol dependence can have many serious effects on the brain, liver, and other organs of the body, some of which can lead to death.
Alprazolam: A benzodiazepine sedative that causes dose-related depression of the central nervous system. Alprazolam is useful in treating anxiety, panic attacks, insomnia, and muscle spasms. The brand name is Xanax. A generic version is available.
Atria: The plural of atrium.
Atrial: Pertaining to the atria, the upper chambers of the heart, as in atrial fibrillation and atrial septal defect.
Atrial fibrillation: An abnormal and irregular heart rhythm in which electrical signals are generated chaotically throughout the upper chambers (atria) of the heart. Many people with atrial fibrillation have no symptoms. Among those who do, the most common symptom is an uncomfortable awareness of the rapid and irregular heartbeat (palpitations). Atrial fibrillation can promote the formation of blood clots that travel from the heart to the brain, resulting in stroke. Treatment of atrial fibrillation involves risk-factor control, use of medications to slow the heart rate and/or convert the heart to
Atrial flutter: Well-organized but overly rapid contractions of the atrium of the heart (usually at a rate of 250-350 contractions per minute).
Breast milk: Milk from the breast. Human milk contains a balance of nutrients that closely matches infant requirements for brain development, growth and a healthy immune system. Human milk also contains immunologic agents and other compounds that act against viruses, bacteria, and parasites. Since an infant's immune system is not fully developed until age 2, human milk provides a distinct advantage over formula.
Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bone by cells called osteoblasts and removed from bone by cells called osteoclasts. Calcium is essential for healthy bones and is also important for muscle contraction, heart action, and normal blood clotting. Food sources of calcium include dairy foods; some leafy green vegetables, such as broccoli and collards; canned salmon; clams; oysters; calcium-fortified foods; and soy foods, such as tofu. According to the National Academy of Sciences, adequate intake of calcium is 1 gram daily for both men and women. The upper limit for calcium intake is 2.5 grams daily.
Chest: The area of the body located between the neck and the abdomen. The chest contains the lungs, the heart, and part of the aorta. The walls of the chest are supported by the dorsal vertebrae, the ribs, and the sternum. Also known as thorax.
Chest pain: Pain in the chest that can be a result of many things, including angina, heart attack (coronary occlusion), and other important diseases. Chest pain is a warning to seek medical attention, so one should try not to ignore chest pain and 'work through it.'
Congestive heart failure: Inability of the heart to keep up with the demands on it, with failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs, such as the brain, liver, and kidneys. Abbreviated CHF. CHF may be due to failure of the right or left ventricle, or both. The symptoms can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling (edema), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart. The many causes of CHF include coronary artery disease leading to heart attacks and heart muscle (myocardium) weakness; primary heart muscle weakness from viral infections or toxins, such as prolonged alcohol exposure; heart valve disease causing heart muscle weakness due to too much leaking of blood or causing heart muscle stiffness from a blocked valve; hyperthyroidism; and high blood pressure.
Contraction: The tightening and shortening of a muscle.
Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo.
Dysfunction: Difficult function or abnormal function.
Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions, converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
FDA: Food and Drug Administration.
Flutter: Flutter is a rapid vibration or pulsation. The difference between flutter and fibrillation is that flutter is well organized while fibrillation is not.
Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.
Headache: A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
Heart: The muscle that pumps blood received from veins into arteries throughout the body. The heart is positioned in the chest behind the sternum (breastbone); in front of the trachea, esophagus, and aorta; and above the diaphragm. A normal heart is about the size of a closed fist and weighs about 298 grams or 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest, with the balance in the right side of the chest. The heart is composed of specialized cardiac muscle, and it is four-chambered, with a right atrium and ventricle, and an anatomically separate left atrium and ventricle. The blood flows from the systemic veins into the right atrium, thence to the right ventricle, from which it is pumped to the lungs and then returned into the left atrium, thence to the left ventricle, from which it is driven into the systemic arteries. The heart is thus functionally composed of two hearts: the right heart and the left heart. The right heart consists of the right atrium, which receives deoxygenated blood from the body, and the right ventricle, which pumps the deoxygenated blood to the lungs under low pressure; and the left heart, which consists of the left atrium, which receives oxygenated blood from the lung, and the left ventricle, which pumps the oxygenated blood out to the body under high pressure.
Heart block: A blockage in the conduction of the normal electrical impulses in the heart. Heart block is not uncommon and is detected with an electrocardiogram. Heart block occurs from degeneration or scarring of the electrical pathways in the heart muscle, either naturally or as a result of disease. Heart block typically requires no treatment, but can be a factor in the decision of whether or not to put a pacemaker in a heart that is failing or irregularly beating.
Heart failure: Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling (edema), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
Heart rate: The number of heartbeats per unit of time, usually per minute. The heart rate is based on the number of contractions of the ventricles (the lower chambers of the heart). The heart rate may be too fast (tachycardia) or too slow (bradycardia). The pulse is a bulge of an artery from waves of blood that course through the blood vessels each time the heart beats. The pulse is often taken at the wrist to estimate the heart rate.
Infant: A young baby, from birth to 12 months of age.
Kidney: One of a pair of organs located in the right and left side of the abdomen. The kidneys remove waste products from the blood and produce urine. As blood flows through the kidneys, the kidneys filter waste products, chemicals, and unneeded water from the blood. Urine collects in the middle of each kidney, in an area called the renal pelvis. It then drains from the kidney through a long tube, the ureter, to the bladder, where it is stored until elimination. The kidneys also make substances that help control blood pressure and regulate the formation of red blood cells.
Magnesium: A mineral involved in many processes in the body including nerve signaling, the building of healthy bones, and normal muscle contraction. About 350 enzymes are known to depend on magnesium.
Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Nausea: Stomach queasiness, the urge to vomit. Nausea can be brought on by many causes, including systemic illnesses (such as influenza), medications, pain, and inner ear disease.
Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.
Oxygen: The odorless gas that is present in the air and necessary to maintain life. Oxygen may be given in a medical setting, either to reduce the volume of other gases in the blood or as a vehicle for delivering anesthetics in gas form. It can be delivered via nasal tubes, an oxygen mask, or an oxygen tent. Patients with lung disease or damage may need to use portable oxygen devices on a temporary or permanent basis.
Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
Potassium: The major positive ion (cation) found inside cells. The chemical notation for potassium is K+. The proper level of potassium is essential for normal cell function. An abnormal increase in potassium (hyperkalemia) or decrease in potassium (hypokalemia) can profoundly affect the nervous system and heart, and when extreme, can be fatal. The normal blood potassium level is 3.5'5.0 milliEquivalents/liter (mEq/L), or 3.5 international units.
Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
Pregnant: The state of carrying a developing fetus within the body.
Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.
Rash: Breaking out (eruption) of the skin. A rash can be caused by an underlying medical condition, hormonal cycles, allergies, or contact with irritating substances. Treatment depends on the underlying cause of the rash. Medically, a rash is referred to as an exanthem.
Sodium: The major positive ion (cation) in the fluid surrounding cells in the body. The chemical notation for sodium is Na+. When sodium is combined with chloride, the resulting substance is a crystal called table salt. Excess dietary sodium is largely excreted in the urine, but too much salt in the diet tends to increase the blood pressure. Too much or too little sodium in the blood (called hypernatremia or hyponatremia respectively) can cause cells to malfunction, and extremes can be fatal. Normal blood sodium level is 135'145 milliEquivalents/liter (mEq/L) or 135'145 millimoles/liter (mmol/L) in international units.
Tachycardia: A rapid heart rate, usually defined as greater than 100 beats per minute.
Therapeutic: Relating to therapeutics, the branch of medicine that is concerned specifically with the treatment of disease. The therapeutic dose of a drug is the amount needed to treat a disease.
Thyroid: 1. The thyroid gland. Also, pertaining to the thyroid gland. 2. A preparation of the thyroid gland used to treat hypothyroidism. 3. Shaped like a shield. (The thyroid gland was so-named by Thomas Wharton in 1656 because it was shaped like an ancient Greek shield.)
Thyroid hormones: Chemical substances made by the thyroid gland, which is located in the front of the neck. This gland uses iodine to make thyroid hormones, which are essential for the function of every cell in the body. They help regulate growth and the rate of chemical reactions (metabolism), and are involved in the circadian rhythms that govern sleep, among other essential functions.
Toxicity: The degree to which a substance (a toxin or poison) can harm humans or animals. Acute toxicity involves harmful effects in an organism through a single or short-term exposure. Subchronic toxicity is the ability of a toxic substance to cause effects for more than one year but less than the lifetime of the exposed organism. Chronic toxicity is the ability of a substance or mixture of substances to cause harmful effects over an extended period, usually upon repeated or continuous exposure, sometimes lasting for the entire life of the exposed organism.
Ventricular: Pertaining to the ventricles, the lower chambers of the heart, as in ventricular fibrillation and ventricular septal defect.
Xanax: See: Alprazolam.
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