Down Syndrome (cont.)
IN THIS ARTICLE
What Increases Your Risk
Certain things increase the chance that you will have a baby with Down syndrome. These are called risk factors. Risk factors may be different based on the type of Down syndrome.
Trisomy 21 is the most common type of Down syndrome. People with this type have an extra chromosome (47 instead of 46) in every cell. Risk factors for this type include:
This type of Down syndrome is caused by only some cells producing 47 chromosomes. Mosaicism affects up to 3 out of 100 people who have Down syndrome.3 Risk factors for mosaicism are similar to those for trisomy 21.
Translocation type is the only type of Down syndrome that may be passed through families, but most of the time it happens randomly. A person with this type has 46 chromosomes, but part of one chromosome breaks and then attaches to a different chromosome. Up to 4 out of 100 people with Down syndrome have the translocation type.4
You may be a carrier of the translocation chromosome if you have:
If you are thinking about becoming pregnant and you're at risk for having a child with Down syndrome, you may want to see a geneticist or genetic counselor. They can help you understand your risk and work with you on genetic testing.
eMedicineHealth Medical Reference from Healthwise
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