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Down Syndrome (cont.)

Outlook

The overall outlook for individuals with Down syndrome has improved dramatically in recent years due to better medical treatment and social inclusion. However, life expectancy is still reduced compared to the normal population.

Congenital heart disease is the major cause for early death.

Many people with Down syndrome show signs of dementia and symptoms of Alzheimer's disease by age 40 years.

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Must Read Articles Related to Down Syndrome

Alzheimer's Disease in Individuals With Down Syndrome
Alzheimer's Disease in Down Syndrome Alzheimer's disease (AD) is the most common form of dementia (see Dementia Overview for more information). The disease is progressive, and the brain degenerates...learn more >>
Cognitive Deficits
Cognitive Deficits Cognitive deficits (intellectual disability) begin in childhood and cause impaired ability to learn and function. Impairment level is categorized as mild, moder...learn more >>

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Read What Your Physician is Reading on Medscape

Down Syndrome »

In 1866, Down described clinical characteristics of the syndrome that now bears his name.

Read More on Medscape Reference »


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