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Down Syndrome (cont.)

Adults with Down Syndrome

Adults with Down syndrome age prematurely. This leads to an increased risk for memory loss, dementia, late-onset seizures (tonic-clonic seizures in particular), and hypothyroidism. Many individuals will show signs of dementia and develop early-onset Alzheimer's disease by age 40.  By the age of 60, 50%-70% of adults with Down syndrome will develop Alzheimer's disease. Since individuals with Down syndrome are already cognitively impaired, it is challenging to diagnose dementia in this population.

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Down Syndrome »

In 1866, Down described clinical characteristics of the syndrome that now bears his name.

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