acetaminophen and diphenhydramine (cont.)
IN THIS ARTICLE
- What is acetaminophen and diphenhydramine (Aceta-Gesic, Anacin P.M. Aspirin Free, Coricidin Night Time Cold Relief, Excedrin PM, Excedrin PM Caplet, Excedrin PM Express Gels, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Pain Relief PM Extra Strength, Percogesic Extra Strength, Percogesic Original Strength, Tylenol Cold Relief Caplet, Tylenol Cold Relief Nighttime, Tylenol Cold Relief Nighttime Caplet, Tylenol Extra Strength PM, Tylenol Extra Strength PM Rapid Release Gelcaps, Tylenol Extra Strength PM Vanilla Caplet, Tylenol PM, Tylenol Sore Throat Nighttime, Unisom with Pain Relief)?
- What are the possible side effects of acetaminophen and diphenhydramine?
- What is the most important information I should know about acetaminophen and diphenhydramine?
- What should I discuss with my healthcare provider before taking acetaminophen and diphenhydramine?
- How should I take acetaminophen and diphenhydramine?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking acetaminophen and diphenhydramine?
- What other drugs will affect acetaminophen and diphenhydramine?
- Where can I get more information?
What happens if I miss a dose?
Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.
The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.
What should I avoid while taking acetaminophen and diphenhydramine?
Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.
Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect acetaminophen and diphenhydramine?
Taking this medicine with other drugs that make you sleepy or slow your breathing can increase these effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Ask a doctor or pharmacist if it is safe for you to use acetaminophen and diphenhydramine if you are also using any of the following drugs:
- acetaminophen (Tylenol);
- diphenhydramine (Benadryl) applied to the skin;
- leflunomide, teriflunomide;
- warfarin, Coumadin;
- an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;
- birth control pills or hormone replacement therapy;
- bladder or urinary medicines such as darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin;
- bronchodilators such as ipratropium or tiotropium;
- cholesterol-lowering medications--Crestor, Lipitor, Pravachol, Simcor, Vytorin, Zocor, and others;
- gout or arthritis medications (including gold injections);
- heart or blood pressure medication;
- HIV or AIDS medications;
- medication for Parkinson's disease;
- medication to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;
- medicines to treat mental illness;
- an NSAID (non-steroidal anti-inflammatory drug)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, others;
- seizure medication--carbamazepine, phenytoin, and others; or
- steroids (prednisone and others).
This list is not complete. Other drugs may interact with acetaminophen and diphenhydramine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Where can I get more information?
Your pharmacist can provide more information about acetaminophen and diphenhydramine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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