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What happens if I miss a dose (Ultracet)?

Since pain medicine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Ultracet)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An acetaminophen and tramadol overdose can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include drowsiness, shallow breathing, slow heartbeat, extreme weakness, sweating, cold or clammy skin, feeling light-headed, fainting, seizure, or coma.

What should I avoid while taking acetaminophen and tramadol (Ultracet)?

Do not drink alcohol while you are taking acetaminophen and tramadol. Alcohol may cause a dangerous decrease in your breathing when used together with acetaminophen and tramadol. Alcohol may also increase your risk of liver damage while taking acetaminophen.

Acetaminophen and tramadol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What other drugs will affect acetaminophen and tramadol (Ultracet)?

Cold or allergy medicine, sedatives, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tramadol. Tell your doctor if you regularly use any of these medicines, or any narcotic pain medicine.

The following drugs can interact with acetaminophen and tramadol. Tell your doctor if you are using any of these:

• carbamazepine (Carbatrol, Equetro, Tegretol);
• warfarin (Coumadin, Jantoven);
• digoxin (Lanoxin, Lanoxicaps);
• ketoconazole (Nizoral);
• erythromycin (E-Mycin, E.E.S., Ery-Tab);
• rifampin (Rifadin, Rimactane, Rifater);
• quinidine (Quin-G);
• St. John's wort;
• sumatriptan (Imitrex, Treximet) and other migraine headache medicines;
• an antidepressant such as amitriptyline (Elavil), citalopram (Celexa), desipramine (Norpramin), fluoxetine (Prozac, Sarafem), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft); or
• drugs to treat high blood pressure or a prostate disorder, such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin), tamsulosin (Flomax).

This list is not complete and other drugs may interact with acetaminophen and tramadol. Tell your doctor about all medications you use. This includes prescription, over the counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about acetaminophen and tramadol.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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