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Medications and Drugs

Brand Names: Panlor SS, Trezix, Zerlor

Generic Name: acetaminophen, caffeine, and dihydrocodeine (Pronunciation: a SEET a MIN oh fen, KAF een, dye HYE droe KOE deen)

What is acetaminophen, caffeine, and dihydrocodeine (Panlor SS, Trezix, Zerlor)?

Dihydrocodeine is an opioid pain medication. An opioid is sometimes called a narcotic.

Acetaminophen is a less potent pain reliever that increases the effects of dihydrocodeine.

Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

The combination of acetaminophen, caffeine, and dihydrocodeine is used to relieve moderate to severe pain.

Acetaminophen, caffeine, and dihydrocodeine may also be used for purposes not listed in this medication guide.

What are the possible side effects of acetaminophen, caffeine, and dihydrocodeine (Panlor SS, Trezix, Zerlor)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using acetaminophen, caffeine, and dihydrocodeine and call your doctor at once if you have a serious side effect such as:

  • shallow breathing, slow heartbeat;
  • fast or pounding heart rate, feeling light-headed, fainting;
  • confusion, hallucinations, unusual thoughts or behavior;
  • muscle twitching;
  • problems with urination;
  • easy bruising or bleeding; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects include:

  • feeling dizzy or drowsy, shaky or agitated;
  • mild nausea, vomiting, upset stomach; constipation, diarrhea;
  • mood changes, sleep problems (insomnia);
  • sweating, urinating more than usual;
  • ringing in your ears, blurred vision; or
  • dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetaminophen, caffeine, and dihydrocodeine (Panlor SS, Trezix, Zerlor)?

Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Dihydrocodeine may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how acetaminophen, caffeine, and dihydrocodeine will affect you.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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