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Medications and Drugs

Brand Names: Coricidin HBP Maximum Strength Flu, Mapap Cough & Sinus Formula, Triaminic Flu Cough & Fever, Triaminic Multi-Symptom Fever, Tylenol Childrens Plus Cough & Runny Nose

Generic Name: acetaminophen, chlorpheniramine, and dextromethorphan (Pronunciation: a SEET a MIN oh fen, klor fen IR a meen, dex troe meth OR fan)

What is acetaminophen, chlorpheniramine, and dextromethorphan (Coricidin HBP Maximum Strength Flu, Mapap Cough & Sinus Formula, Triaminic Flu Cough & Fever, Triaminic Multi-Symptom Fever, Tylenol Childrens Plus Cough & Runny Nose)?

Acetaminophen is a pain reliever and fever reducer.

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

The combination of acetaminophen, chlorpheniramine, and dextromethorphan is used to treat runny nose, cough, and pain or fever caused by the common cold or flu.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, chlorpheniramine, and dextromethorphan may also be used for other purposes not listed in this medication guide.

What are the possible side effects of acetaminophen, chlorpheniramine, and dextromethorphan (Coricidin HBP Maximum Strength Flu, Mapap Cough & Sinus Formula, Triaminic Flu Cough & Fever, Triaminic Multi-Symptom Fever, Tylenol Childrens Plus Cough & Runny Nose)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeats;
  • confusion, hallucinations, unusual thoughts or behavior;
  • severe dizziness, anxiety, restless feeling, or nervousness;
  • urinating less than usual or not at all;
  • easy bruising or bleeding, unusual weakness; or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • dry eyes, blurred vision;
  • dry mouth, upset stomach, constipation;
  • warmth, tingling, or redness under your skin;
  • dizziness, drowsiness;
  • restless or excitability (especially in children);
  • sleep problems (insomnia);
  • problems with memory or concentration;
  • ringing in your ears; or
  • mild skin rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetaminophen, chlorpheniramine, and dextromethorphan (Coricidin HBP Maximum Strength Flu, Mapap Cough & Sinus Formula, Triaminic Flu Cough & Fever, Triaminic Multi-Symptom Fever, Tylenol Childrens Plus Cough & Runny Nose)?

Do not take this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take dextromethorphan before the MAO inhibitor has cleared from your body.

Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. If you drink more than three alcoholic beverages per day, do not take this medication without your doctor's advice, and never take more than 2 grams (2000 mg) of acetaminophen per day.

Do not use any other cough, cold, or allergy medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen (sometimes abbreviated as "APAP"), chlorpheniramine, or dextromethorphan.

Do not give this medicine to a child without a doctor's advice. Death can occur from the misuse of cough or cold medicine in very young children. Always ask your doctor before treating a cough or cold in a child.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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