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Medications and Drugs

Brand Names: Lithostat

Generic Name: acetohydroxamic acid (Pronunciation: a SEET oh HYE drox AM ik AS id)

What is acetohydroxamic acid (Lithostat)?

Acetohydroxamic acid works by preventing bacteria from increasing ammonia levels in urine. Increased ammonia in urine can lead to a certain type of kidney stone.

Acetohydroxamic acid is used together with antibiotics to treat bladder infections caused by bacteria that can increase ammonia levels in the urine.

Acetohydroxamic acid may also be used for other purposes not listed in this medication guide.

What are the possible side effects of acetohydroxamic acid (Lithostat)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • chest pain, fast or pounding heartbeats;
  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;
  • mood changes, confusion, anxiety;
  • tremors or shaking;
  • easy bruising or bleeding;
  • sore throat, body aches, flu symptoms; or
  • pain or swelling in one or both legs.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetohydroxamic acid (Lithostat)?

This medication can cause birth defects. Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Before using acetohydroxamic acid, tell your doctor if you have kidney disease, a history of blood clot or stroke, hemolytic anemia (a lack of red blood cells), or a weak immune system.

Take acetohydroxamic acid on an empty stomach, at least 1 hour before or 2 hours after a meal. Acetohydroxamic acid is usually taken 3 or 4 times daily. Follow your doctor's instructions.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Acetohydroxamic acid is not an antibiotic and will not treat a bacterial infection alone. Take your antibiotic medication as directed.

Avoid drinking alcohol. Drinking alcohol while taking this medication can cause you to have warmth, redness, or tingling under your skin. This may be an unpleasant side effect.

Call your doctor at once if you have a serious side effect such as chest pain, fast or pounding heartbeats, pale or yellowed skin, dark colored urine, fever, confusion or weakness, mood changes, confusion, anxiety, tremors or shaking, easy bruising or bleeding, flu symptoms, or pain or swelling in one or both legs.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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