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Medications and Drugs

Brand Names: Epiduo

Generic Name: adapalene and benzoyl peroxide (topical) (Pronunciation: a DAP a leen and BEN zoyl per OX ide)

What is adapalene and benzoyl peroxide topical (Epiduo)?

Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect, which allows excess oils and dirt to be easily washed away from the skin.

Adapalene is a medication similar to vitamin A. It helps the skin renew itself.

The combination of adapalene and benzoyl peroxide topical (for the skin) is used to treat acne in people who are at least 12 years old.

Adapalene and benzoyl peroxide topical may also be used for other purposes not listed in this medication guide.

What are the possible side effects of adapalene and benzoyl peroxide topical (Epiduo)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

During your first 4 weeks of using adapalene and benzoyl peroxide topical, your skin may be dry, red, or scaly. You may also feel some burning or stinging. Call your doctor if these side effects are severe.

Less serious side effects may include mild itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about adapalene and benzoyl peroxide topical (Epiduo)?

Before using this medication, tell your doctor about all other medicated skin products you are using. Using more than one acne medication at a time could cause severe skin irritation.

Avoid getting this medication in your mouth, nose, or eyes, or on your lips. If it does get into any of these areas, rinse with water. Do not use adapalene and benzoyl peroxide topical on sunburned, windburned, dry, chapped, irritated, or broken skin. Also avoid using adapalene and benzoyl peroxide topical on wounds or on areas of eczema. Wait until these conditions have healed before using this medication.

Avoid using skin products that can cause dryness or irritation, such as harsh soaps, shampoos, or skin cleansers, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

Do not use other medicated skin products unless your doctor has told you to.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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