Medications and Drugs
Brand Names: Proleukin
Generic Name: aldesleukin (Pronunciation: AL des LOO kin)
What is aldesleukin (Proleukin)?
Aldesleukin is a cancer medication that interferes with tumor growth.
Aldesleukin is used to treat kidney cancer or skin cancer than has spread to other parts of the body.
Aldesleukin may also be used for other purposes not listed in this medication guide.
What are the possible side effects of aldesleukin (Proleukin)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about aldesleukin (Proleukin)?
You should not receive this medication if you are allergic to aldesleukin or interleukin-2, or if you have a bacterial infection, if you have received an organ transplant, or if you have recently had abnormal lung or heart function tests.
You may not be able to receive aldesleukin if prior treatment with this medication caused chest pain, irregular heart rhythm, a build-up of fluid around your heart, kidney failure, seizures, psychosis, stomach or intestinal bleeding, or if you needed a breathing tube.
Before you receive aldesleukin, tell your doctor if you have a heart disorder or history of heart attack, breathing problems, kidney or liver disease, gallbladder disease, high levels of calcium in your blood, a thyroid disorder, diabetes, seizures, mental illness, neurologic problems, or an autoimmune disorder (arthritis, Crohn's disease, scleroderma, myasthenia gravis, or skin disorder).
There are many other drugs that can interact with aldesleukin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
If you need to have any type of x-ray or other scan using a contrast agent (a dye that is used to help blood vessels, organs, and other non-bony tissues appear more clearly on the x-ray or scan), be sure the doctor knows ahead of time if you have recently received aldesleukin. Some people treated with aldesleukin or similar medication have had unusual allergic reactions to contrast agents used within weeks to several months later.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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