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What should I discuss with my healthcare provider before receiving aldesleukin (Proleukin)?
You should not receive this medication if you are allergic to aldesleukin or interleukin-2, or if you have:
You may not be able to receive aldesleukin if you have had any of these side effects while receiving aldesleukin in the past:
To make sure you can safely receive aldesleukin, tell your doctor if you have any of these other conditions:
FDA pregnancy category C. It is not known whether aldesleukin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether aldesleukin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How is aldesleukin given (Proleukin)?
Aldesleukin is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Aldesleukin must be given slowly, and the IV infusion can take at least 15 minutes to complete.
Aldesleukin is usually given every 8 hours for up to 5 days, followed by a 9-day rest period and then repeated.
Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving aldesleukin. Your blood will also need to be tested daily during treatment, and you may also need chest x-rays.
After 4 weeks off the medication, your doctor will examine you to determine if you need to be treated again with aldesleukin.
If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, be sure the doctor knows ahead of time if you have recently received aldesleukin. Some people treated with aldesleukin or similar medication have had unusual allergic reactions to contrast agents used within weeks to several months later.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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