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Medications and Drugs

Brand Names: Panretin

Generic Name: alitretinoin topical (Pronunciation: ah lih TREH tin oyn)

What is alitretinoin topical (Panretin)?

Alitretinoin is a topical retinoid. Alitretinoin affects the growth and development of skin cells.

Alitretinoin topical is used to treat skin lesions caused by AIDS-related Kaposi's sarcoma.

Alitretinoin topical may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of alitretinoin topical (Panretin)?

Serious side effects are not likely to occur. Stop using alitretinoin topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives).

If you experience any of the following less serious side effects at the application site(s), continue to use alitretinoin topical and notify your doctor

  • redness;
  • itching;
  • irritation;
  • warmth;
  • burning, stinging, or pain;
  • rash;
  • peeling;
  • swelling or inflammation;
  • numbness or tingling;
  • cracking, crusting, or scabbing; or
  • drainage.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about alitretinoin topical (Panretin)?

Avoid prolonged exposure to sunlight. Alitretinoin topical may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Do not use products that contain DEET (N, N-diethyl-m-toluamide), a common component of insect repellent products, while using alitretinoin topical. There is an increased risk of harmful effects from DEET when it is used with alitretinoin topical.

Do not cover the treated lesions with any type of occlusive dressing (a dressing that does not allow air to circulate to the area).

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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