amiodarone (injection) (cont.)
What happens if I miss a dose (Nexterone)?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose (Nexterone)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include weakness, slow heart rate, feeling light-headed, or fainting.
What should I avoid while using amiodarone injection (Nexterone)?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Grapefruit and grapefruit juice may interact with amiodarone and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.
Avoid exposure to sunlight or tanning beds. Amiodarone can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
What other drugs will affect amiodarone injection (Nexterone)?
Many drugs can interact with amiodarone. Below is only a partial list. Tell your doctor if you are using:
- cimetidine (Tagamet);
- clopidogrel (Plavix);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- dextromethorphan (an over-the-counter cough medicine);
- digoxin (digitalis, Lanoxin, Lanoxicaps);
- fentanyl (Abstral, Actiq, Fentora, Duragesic, Ionsys, Lazanda, Onsolis);
- loratadine (Claritin Alavert);
- phenytoin (Dilantin);
- St. John's wort;
- a blood thinner such as warfarin (Coumadin, Jantoven);
- a diuretic (water pill);
- an antibiotic such as azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), rifampin (Rifadin, Rimactane, Rifater, Rifamate), telithromycin (Ketek), and others;
- an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
- an antidepressant such as nefazodone or trazodone (Desyrel);
- arthritis medication such as diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze) or piroxicam (Feldene);
- cholesterol-lowering medicines such as cholestyramine (Prevalite, Questran), atorvastatin (Lipitor, Caduet), lovastatin (Mevacor, Altoprev, Advicor), rosuvastatin (Crestor), simvastatin (Zocor, Simcor, Vytorin, Juvisync), and others;
- heart or blood pressure medication such as diltiazem (Cardizem, Cartia), nicardipine (Cardene), propranolol (Inderal, InnoPran), verapamil (Calan, Covera, Isoptin, Verelan), and others;
- heart rhythm medication such as disopyramide (Norpace), flecainide (Tambocor), quinidine (Quin-G), or procainamide (Procan, Pronestyl);
- insulin or diabetes medication you take by mouth; or
- medication to treat HIV or AIDS.
This list is not complete and there are many other medicines that can cause serious drug interactions with amiodarone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Amiodarone takes a long time to completely clear from your body, and drug interactions are possible for up to several months after you stop using amiodarone injection. Talk to your doctor before taking any medication during this time. Keep track of how long it has been since your last dose of amiodarone.
Where can I get more information?
Your doctor or pharmacist can provide more information about amiodarone injection.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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