amiodarone (oral) (cont.)
What happens if I miss a dose (Cordarone, Pacerone)?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Cordarone, Pacerone)?
Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include weakness, slow heart rate, feeling light-headed, or fainting.
What should I avoid while taking amiodarone (Cordarone, Pacerone)?
Amiodarone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Grapefruit and grapefruit juice may interact with amiodarone and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Amiodarone can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
What other drugs will affect amiodarone (Cordarone, Pacerone)?
Many drugs can interact with amiodarone. Below is only a partial list. Tell your doctor if you are using:
- cimetidine (Tagamet);
- clopidogrel (Plavix);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- dextromethorphan (an over-the-counter cough medicine);
- diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze);
- digoxin (digitalis, Lanoxin, Lanoxicaps);
- loratadine (Claritin Alavert);
- St. John's wort;
- an antidepressant;
- a blood thinner such as warfarin (Coumadin);
- a diuretic (water pill);
- insulin or diabetes medication you take by mouth;
- narcotic pain medication;
- medication to treat HIV or AIDS;
- an antibiotic such as azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), rifampin (Rifadin, Rimactane, Rifater, Rifamate), telithromycin (Ketek), and others;
- an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
- a beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta, Ziac), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others;
- cholesterol-lowering medicines such as cholestyramine (Prevalite, Questran), atorvastatin (Lipitor), simvastatin (Zocor), lovastatin (Mevacor), pravastatin (Pravachol), or fluvastatin (Lescol);
- heart rhythm medication such as disopyramide (Norpace), quinidine (Quinaglute, Quinidex), or procainamide (Procan, Pronestyl);
- heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), nifedipine (Procardia, Adalat), verapamil (Calan, Covera, Isoptin, Verelan), and others; or
- seizure medication such as carbamazepine (Carbatrol, Tegretol), phenytoin (Dilantin), and others.
This list is not complete and there are many other medicines that can cause serious drug interactions with amiodarone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about amiodarone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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