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Medications and Drugs

Brand Names: Lotrel

Generic Name: amlodipine and benazepril (Pronunciation: am LOE di peen and ben AY ze pril)

What is amlodipine and benazepril (Lotrel)?

Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow.

Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Benazepril also widens blood vessels and also prevents the body from retaining water.

Amlodipine and benazepril is a combination medicine used to treat high blood pressure (hypertension).

Amlodipine and benazepril may also be used for purposes not listed in this medication guide.

Amlodipine-Benazepril 10 mg-20 mg-TEV

capsule, blue, imprinted with TEVA 7373

Amlodipine-Benazepril 10 mg-40 mg-TEV

capsule, blue, imprinted with TEVA, 7671

Amlodipine-Benazepril 2.5 mg-10 mg-TEV

capsule, white, imprinted with TEVA, 7370

Amlodipine-Benazepril 5 mg-10 mg-TEV

capsule, orange/white, imprinted with TEVA, 7371

Amlodipine-Benazepril 5 mg-20 mg-TEV

capsule, pink/white, imprinted with TEVA 7372

Amlodipine-Benazepril 5 mg-40 mg-TEV

capsule, blue, imprinted with TEVA, 7670

Lotrel 10 mg-20 mg

capsule, purple, imprinted with LOTREL 0364

Lotrel 10-40 mg

capsule, blue, imprinted with Lotrel 0379

Lotrel 2.5-10mg

capsule, white, imprinted with LOTREL 2255

Lotrel 5 mg-10 mg

capsule, brown, imprinted with LOTREL 2260

Lotrel 5-10mg

capsule, brown, imprinted with LOTREL 2260

Lotrel 5-20

capsule, pink, imprinted with LOTREL 2265

Lotrel 5-40 mg

capsule, blue, imprinted with Lotrel, 0384

What are the possible side effects of amlodipine and benazepril (Lotrel)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American.

Some side effects of amlodipine and benazepril may not occur until after you have been using the medication for several months.

Call your doctor at once if you have:

  • feeling like you might pass out;
  • nausea, upper stomach pain, itching, unusual weakness or tired feeling, jaundice (yellowing of the skin or eyes);
  • swelling in your hands or feet, rapid weight gain;
  • new or worsened chest pain;
  • fever, chills, sore throat, body aches, flu symptoms; or
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling).

Other common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about amlodipine and benazepril (Lotrel)?

Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Amlodipine and benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.

You should not use this medication if you are allergic to amlodipine (Norvasc) or benazepril (Lotensin), or if you have ever had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction).

Before you use amlodipine and benazepril, tell your doctor about all your other medical conditions and allergies. Also make sure your doctor knows if you are pregnant or breast-feeding. In some cases, you may not be able to use amlodipine and benazepril, or you may need a dose adjustment or special precautions.

Certain other drugs may interact with amlodipine and benazepril or should not be used at the same time. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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