Medications and Drugs

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Brand Names: Tribenzor

Generic Name: amlodipine, hydrochlorothiazide, and olmesartan (Pronunciation: am LOE di peen, HYE droe KLOR oh THYE a zide, and OL me SAR tan)

• What is amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?
• What are the possible side effects of amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?
• What is the most important information I should know about amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?
• What should I discuss with my health care provider before taking amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?
• How should I take amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?
• What happens if I miss a dose (Tribenzor)?
• What happens if I overdose (Tribenzor)?
• What should I avoid while taking amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?
• What other drugs will affect amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?
• Where can I get more information?

What is amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?

Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow.

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Olmesartan is an angiotensin II receptor antagonist. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

The combination of amlodipine, hydrochlorothiazide, and olmesartan is used to treat high blood pressure (hypertension). This medication is usually given after others have been tried without successful treatment of hypertension.

Amlodipine, hydrochlorothiazide, and olmesartan may also be used for purposes not listed in this medication guide.

What are the possible side effects of amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any other serious side effects, such as:

• eye pain, vision problems;
• feeling like you might pass out;
• swelling in your hands, ankles, or feet;
• urinating less than usual or not at all;
• pain or burning when you urinate;
• joint pain or swelling with fever, swollen glands, muscle aches, unusual thoughts or behavior, patchy skin color, red spots, or skin rash on your face;
• headache, trouble concentrating, memory problems, weakness, feeling unsteady, hallucinations, fainting, seizure, shallow breathing;
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; or
• electrolyte imbalance--nausea, loss of appetite, uneven heart rate, extreme thirst, increased urination, leg discomfort, jerking muscle movements, muscle weakness or limp feeling, confusion, and feeling tired or restless.

Less serious side effects may include:

• dizziness;
• diarrhea;
• muscle spasms;
• cold symptoms such as stuffy nose, sneezing, sore throat; or
• flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about amlodipine, hydrochlorothiazide, and olmesartan (Tribenzor)?

You should not use this medication if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic), or olmesartan (Benicar), or if you have severe kidney disease, if you are unable to urinate, or if you are allergic to sulfa drugs.

Before you take amlodipine, hydrochlorothiazide, and olmesartan, tell your doctor if you have kidney or liver disease, congestive heart failure, angina (chest pain), severe coronary artery disease, glaucoma, lupus, diabetes, a penicillin allergy, if you are dehydrated, or if you are vomiting or having diarrhea.

You should not breast-feed while you are taking this medication.

Call your doctor at once if you have any signs of an electrolyte imbalance, such as: headache, trouble concentrating, memory problems, weakness, feeling unsteady, nausea, loss of appetite, extreme thirst, increased urination, leg discomfort, jerking muscle movements, muscle weakness or limp feeling, shallow breathing, uneven heart rate, confusion, feeling tired or restless, hallucinations, fainting, or seizure.

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