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Medications and Drugs

Brand Names: Prevpac

Generic Name: amoxicillin, clarithromycin, and lansoprazole (Pronunciation: a MOX i SIL in, kla RITH roe MYE sin, LAN soe PRA zole)

What is amoxicillin, clarithromycin, and lansoprazole (Prevpac)?

Amoxicillin is a penicillin antibiotic. Clarithromycin is a macrolide antibiotic. These antibiotics fight bacteria in the body.

Lansoprazole decreases the amount of acid produced in the stomach.

The combination of amoxicillin, clarithromycin, and lansoprazole is used to prevent stomach ulcer caused by infection with Helicobacter pylori (H. pylori).

Amoxicillin, clarithromycin, and lansoprazole may also be used for purposes not listed in this medication guide.

What are the possible side effects of amoxicillin, clarithromycin, and lansoprazole (Prevpac)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • diarrhea that is watery or bloody;
  • signs of new infection, such as fever, chills, body aches, flu symptoms, mouth sores;
  • easy bruising or bleeding, unusual weakness;
  • agitation, confusion, unusual thoughts or behavior;
  • dizziness, fainting, fast or pounding heartbeat; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • unusual or unpleasant taste in your mouth;
  • headache;
  • nausea, vomiting, stomach pain;
  • constipation, dark colored stools;
  • dry mouth, increased thirst; or
  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about amoxicillin, clarithromycin, and lansoprazole (Prevpac)?

You should not take this medication if you are allergic to amoxicillin (Amoxil, Trimox, Dispermox), clarithromycin (Biaxin), lansoprazole (Prevacid), or to certain other antibiotics.

Before you take this medication, tell your doctor if you have kidney or liver disease, myasthenia gravis, or if you are allergic to any drugs.

There are many other drugs that can interact with this medication. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

While you are taking amoxicillin, clarithromycin, and lansoprazole, do not take any of the following medications: ergotamine (Ergomar, Cafergot, Ercaf, Migergot), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), or pimozide (Orap).

A gout medication called colchicine (Colcrys) can interact with clarithromycin and cause serious or life-threatening medical problems. You should not take colchicine during your treatment with amoxicillin, clarithromycin, and lansoprazole, especially if you are an older adult with kidney disease.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Use the pill finder tool on RxList.



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