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What should I discuss with my healthcare provider before taking amoxicillin, clarithromycin, and lansoprazole (Prevpac)?

You should not take this medication if you are allergic to amoxicillin (Amoxil, Trimox, Dispermox), clarithromycin (Biaxin), lansoprazole (Prevacid), or to any of the following antibiotics:

• ampicillin (Omnipen, Principen);
• azithromycin (Zithromax);
• carbenicillin (Geocillin);
• dicloxacillin (Dycill, Dynapen);
• erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin);
• oxacillin (Bactocill);
• penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others);
• telithromycin (Ketek); or
• troleandomycin (Tao).

Taking any of the following medicines together with amoxicillin, clarithromycin, and lansoprazole can cause a life-threatening side effect on your heart:

• cisapride (Propulsid);
• ergotamine (Ergomar, Cafergot, Ercaf, Migergot);
• dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate); or
• pimozide (Orap).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking amoxicillin, clarithromycin, and lansoprazole, tell your doctor if you have:

• kidney disease;
• liver disease;
• myasthenia gravis; or
• if you are allergic to any drugs (especially an antibiotic).

FDA pregnancy category C. Clarithromycin may be harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Amoxicillin can make birth control pills less effective, which may result in pregnancy. Before taking amoxicillin, clarithromycin, and lansoprazole, tell your doctor if you use birth control pills.

Amoxicillin, clarithromycin, and lansoprazole can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take amoxicillin, clarithromycin, and lansoprazole (Prevpac)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Each dose of this combination medication contains 4 pills ( 3 capsules and 1 tablet). Take all 4 pills twice daily before you eat, unless your doctor tells you otherwise.

Do not crush, chew, break, or open the pills. Swallow each pill whole. You may swallow the pills one at a time.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Amoxicillin, clarithromycin, and lansoprazole will not treat a viral infection such as the common cold or flu.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using amoxicillin, clarithromycin, and lansoprazole.

Store this medication at room temperature, away from moisture, heat, and light.

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