Medications and Drugs
Brand Names: AmBisome
Generic Name: amphotericin B liposomal (Pronunciation: am foe TER i sin lye poe SO mal)
What is amphotericin B liposomal (AmBisome)?
Amphotericin B liposomal is an antibiotic that fights fungal infections in the body.
Amphotericin B liposomal is used to treat serious, life-threatening fungal infections, including a certain form of meningitis in people infected with HIV (human immunodeficiency virus).
Amphotericin B liposomal is not for use in treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina.
Amphotericin B liposomal is usually given after other antifungal antibiotics have been tried without successful treatment of symptoms.
Amphotericin B liposomal may also be used for purposes other than those listed in this medication guide.
What are the possible side effects of amphotericin B liposomal (AmBisome)?
Some people receiving an amphotericin B liposomal injection have had a reaction to the infusion (either when the medicine is injected into the vein or within 1 to 3 hours afterward). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, feverish or cold, or if you have a slow heartbeat, chest tightness, or trouble breathing.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor at once if you have any of these serious side effects:
Less serious side effects may also occur, such as:
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about amphotericin B liposomal (AmBisome)?
Do not receive this medication if you are allergic to any formulation of amphotericin B (Abelcet, AmBisome, Amphotec, or Fungizone).
Amphotericin B liposomal is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.
The medicine must be given slowly through an IV infusion, and can take up to 2 hours to complete.
Amphotericin B liposomal may need to be given for up several weeks or months, depending on the infection being treated.
Some people receiving an amphotericin B liposomal injection have had a reaction to the infusion (either when the medicine is injected into the vein or within 1 to 3 hours afterward). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, feverish or cold, or if have a slow heartbeat, chest tightness, or trouble breathing.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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